Diflucan (Fluconazole)

What is Generic Diflucan?

Triazole antifungal agent Diflucan is a medication of a new class of innovative way of combating fungi of various natures. The composition of Diflucan agent has a component with a strong antibiotic exposure - Fluconazole. This substance inhibits the vital processes of fungal microorganisms thereby causing their death. It is worth noting that the medication has no effect on female hormones. The effectiveness of the impact of the active substance Fluconazole was tested for all possible variations of fungal lesions. A special efficiency was obtained in the treatment of opportunistic fungal infections caused by Candida spp.

In what kind of disease treatment Diflucan is helpful?

Based on clinical studies and reviews of doctors drug Diflucan showed itself in the best way in eliminating:

• The most common disease is candidiasis of the genitals (acute, recurrent thrush); for preventive action to significantly reduce the frequency of recurrence of thrush (more than 3 cases per year); as well as for diseases of fungal etiology, it causes inflammation of the foreskin of the penis glans;
• Inflammation of the mucous membranes of the oral cavity and throat provoked by fungi of the genus Candida including during normal operation and depressed functioning of the immune system; to prevent recurrence of oropharyngeal fungal infection caused by fungi of the genus Candida in patients with AIDS;
• Infectious disease caused by a yeast Cryptococcus neoformans, including cryptococcal meningitis and defeat with a different location (lung, dermis), including: in patients with a normally functioning immune system, as well as AIDS patients, and patients with transplanted organs and other subspecies of immunodeficiency;
• In the presence of the fungus kind of genus Candida, in disseminated fungal infection provoked by the fungus of the same kind of genus and other variations of invasive Candida infection;
• As a preventive measure to solve the problem of fungal infections in patients with substandard tumors after cytotoxic chemotherapy or radiotherapy;
• Fungal infections of the dermis, feet, body, genitals, with pityriasis versicolor, onychomycosis and skin candidiasis lesions;
• Severe endemic mycoses in patients with normal immune systems operating at coccidioidomycosis, paracoccidioidomycosis, histoplasmosis and sporotrichosis.

What should I tell my health care provider before I take Generic Diflucan?

It is forbidden to take triazole agent Diflucan in combination with Cisapride, Terfenadine and Astemizole. Furthermore, do not take the above-mentioned drug if you have hypersensitivity to the main components of the drug, as well as to close in the structure of substances.

The antifungal drug Diflucan is forbidden for taking during carrying the fetus except in some cases when a fungal infection may be a threat to the fetus, but the possible benefits of receiving the drug are much higher than the presumed danger. During lactation also is advisable to suspend medication therapy due to ingress of Fluconazole into milk in the same quantity as in the blood.

Patients with the following forms of the disorder should refrain from antifungal therapy with this medication:

• clearly expressed illnesses of the liver;
• rash occurs after the 1st use of the drug;
• occurrence of bubbles and erosion and erythema.

How should I take Diflucan?

This medicament is administered orally as tablets.

Dosage information

On the basis of the official recommendations of the treatment with this agent is allowed to start before the analysis of crop and other clinical procedures. But the scheme of anti-infective therapy should be corrected after getting test results and clinical studies.

The daily dosage of the drug is determined depending on the nature and severity of the fungal infection. In cases of thrush quite effective one-time take of the drug. In fungal infection that requires duplication of medications therapy can be extended to a holistic eliminate of external or clinically significant symptoms of a fungal infection. In cases of recurrent oropharyngeal candidiasis, cryptococcal meningitis and AIDS often spend supportive treatment in order to avoid recurrence of the fungal infection.

What may interact with Diflucan?

In therapy simultaneously with other drugs are observed:

• Contraindicated with Terfenadine with Cisapride at a dose of 400 mg per day and more than the undesirable effects due to the cardiovascular system (a high probability);
• At daily dose of Fluconazole <400 mg combination therapy with Terfenadine is possible with controlling the plasma concentration levels of Terfenadine;
• Increasing of the concentration of benzodiazepines (short-acting) and their psychotropic effects, especially after taking the pill;
• An increase in the blood plasma concentration of active ingredientat the same time with multiple dose of thiazide diuretics;
• Reduction of T1 / 2 of active substance and Rifampicin;
• Promotes an increase in T1 / 2 of oral agents of sulfonylurea; in diabetes it is important to take into account the probability of hypoglycemia;
• It is necessary to monitor the level of concentration of cyclosporine in the blood.

What should I watch for while taking Diflucan?

Considering the hepatotoxic effects it is usually reversible and after completion or termination of therapy, the symptoms disappear. Diflucan should be abolished after the appearance in the course of therapy liver disease symptoms. Fluconazole like other azoles can provoke an increase in the QT interval on the ECG.

Women of childbearing age should use reliable contraception.

At occurrence of rash as a result of side effects of Fluconazole in surface fungal infection you should cancel the drug immediately, in the treatment of systemic or invasive fungal infections is overturned only in bullous lesions or erythema multiforme appearance.

The use of it has no significant effect on the ability to directly manage complex mechanisms and driving.

If you buy Diflucan online then read carefully the instruction in the package.

What side effects may I notice from Generic Diflucan?

CNS:

• dizziness;
• headache pain;
• convulsions;
• insomnia;
• changes in taste;
• tremors;
• drowsiness.

Digestive system:

• nausea;
• bloating;
• diarrhea;
• abdominal pain;
• vomiting;
• constipation;
• indigestion;
• dryness of the mouth;
• hepatitis;
• liver function disorders;
• jaundice;
• hepatotoxicity (probable death);
• hepatocellular damage;
• cholestasis;
• increased serum activity of alkaline phosphatase, bilirubin.

Hematopoietic system:

• neutropenia;
• agranulocytosis.
• leukopenia;
• thrombocytopenia;
• anemia.

Skin:

• Alopecia;
• rash;
• exfoliative skin diseases;
• increased sweating;
• generalized exanthematous pustulosis in acute form.

Allergic reactions:

• hives;
• swelling of the face;
• itching;
• angioedema.

Musculoskeletal system:

• myalgia.

Other:

• asthenia;
• vertigo;
• fever;
• fatigue.

There was a case of drug overdose in a patient with HIV as a result of which appeared paranoid behavior and hallucinations after receiving 8200 mg which required hospitalization. Within 48 hours, his condition returned to normal.

Where can I keep Diflucan?

Diflucan drug is kept in a cool, dry place, quite dark, inaccessible to children at a temperature of 30 ° C.