Its main action is realized at the expense of the active substance Lisinopril. The effect is based on the expansion of the central and peripheral vascular disease (mostly arterial) whereby the normalization of blood pressure occurs.
Additionally, Generic Zestril:
reduces the preload on the heart and pulmonary capillary pressure in the network;
increases minute volume of blood;
increases the resistance to stress the heart muscle in patients suffering from chronic heart failure;
improves blood flow to the heart;
activates blood circulation in the kidneys;
with a long reception drug reduces the hypertrophy of the heart muscle.
Thanks to all of the above it is able to increase the length and quality of life of people suffering from chronic heart failure.
In what kind of disease treatmentZestrilis helpful?
It is used both separately and as part of combination therapy in patients with arterial hypertension of various nature;
Hypertension - indication for Zestril as an additional tool in the treatment of chronic heart failure in patients who are also taking medications such as digitalis drugs and diuretics;
In complex therapy for the prevention of dysfunction of the left ventricle of the heart and heart failure.
What should I tell my health care provider before I takeGeneric Zestril?
If you purchase Generic Zestril then you should know that the absolute contraindications:
Allergic reactions to substances contained in the Generic Zestril;
Previous angioedema (such as caused by the intake of ACE inhibitors and idiopathic);
Children under 6 years;
II and III trimesters of pregnancy (possible teratogenic and toxic effects of Lisinopril).
Reviews of Generic Zestril say that the drug should be used with caution:
In severe pathology and organic disorders of the cardiovascular, urinary, hematopoietic system;
Initially reduced in cases of arterial pressure;
In violation of water-salt metabolism (vomiting and diarrhea, decreased level of sodium in the salt-free diet);
In severe forms of diseases associated with metabolic disorders;
Cerebral vascular system diseases (including stroke, and other cerebrovascular accident);
In the I trimester of pregnancy and lactation (confirmed this on the lack of security);
Elderly people (under the control of renal function) and children up to 18 years.
How should I take Zestril?
Regardless of the disease it is applied once per day before or after a meal. To maintain an optimum concentration of active ingredient in the blood is desirable to take the drug on a regular basis at the same time.
Dosage information
In the first 24 hours after the onset of myocardial infarction - 5 mg one-time. Then, after 24 hours - an additional 5 mg and after 48 hours - an additional 10 mg. Maintenance dose - 10 mg per day. The course of treatment is 6 weeks.
The maximum daily dose for children weighing 20 to 50 kg is 20 mg. For patients over 50 kg - 40 mg but remember that in different diagnosis the maximal dose is different. If you buy Generic Zestril without prescription – read the instruction.
What may interact with Generic Zestril?
Joint reception Zestril with potassium-sparing diuretics as well as products and formulations containing potassium threatens the emergence of an increased level of potassium in the blood. Also in the blood potassium level rises when used along with NSAIDs (ibuprofen). These changes may lead to impaired renal function. With simultaneous use of Zestril and other drugs that reduce the pressure (including nitrates) - their combined hypotensive effect enhanced. The same effect is observed in the interaction with tricyclic antidepressants and neuroleptics.
When used with ethanol Zestril amplifies manifestations of alcohol intoxication. It reduces excretion of lithium, enhances the effect of insulin and sulfonylureas. Therefore, the appointment of these drugs should be under the control of laboratory parameters.
What should I watch for while taking Zestril?
If previously you took diuretics you should abandon their reception at least 2-3 days before the appointment of Zestril.
What side effects may I notice from Generic Zestril?
Note that when receiving Zestril most patients complain of dizziness, weakness, headache, nausea, vomiting, diarrhea, dry cough, orthostatic hypotension, rash and chest pain. In addition to the above are also possible side effects of Generic Zestril from the following organs and systems:
On the cardiovascular system: an excessive fall in blood pressure, acceleration or deceleration rate, conduction disturbances;
Urogenital system: decreased urine output up to anuria, uremia, renal dysfunction, decreased potency;
Changes in the blood and urine analyzes: changes potassium, magnesium, sodium, chlorine, calcium, increase of urea, creatinine, bilirubin, cholesterol and triglycerides;
Other effects: weakness, discomfort and pain in the joints, muscles, fever.
