Tambocor (Flecainide)

It is an antiarrhythmic drug, manufactured by Torrent Pharmaceuticals Limited. It allows you to solve one of the most serious cardiological problems - to stabilize the heart rate and eliminate most of the paroxysmal disturbances. Clinical studies have shown that in the group of patients who took the remedy for 16 weeks, the frequency and number of arrhythmia attacks decreased by almost 80%.

The drug belongs to the category of antiarrhythmic drugs 1C class, which can slow the electrical conductivity of the heart, increasing the refractal period, that is, the resting time of the ventricles.

This medication is virtually continuously connected to the sodium channels and slows down the holding even at low heart rate (that is, at rest). As a result, it exerts a dose-dependent effect on the electrocardiogram, which is expressed in the progressive lengthening of the PR interval and the QRS complex (which reflects the slowing of the rate of exercise) with an insignificant effect on the QT interval (which reflects the minimal effect of flecainide on the refractory period). The drug inhibits conduction in all parts of the heart.

This tool helps the work of the heart, it activates its blood pumping activity and all parts of the heart begin to work synchronously. The drug has been known for over 30 years and has passed the necessary clinical trials. They showed its effectiveness and safety.

The medicinal properties of the drug make it possible to use it for the prevention and therapy of the following diseases:

• Paroxysmal supranventicular tachycardia (all forms);

• Paroxysmal (sudden) form of atrial fibrillation or flutter;

• Ventricular tachycardia, which has been confirmed by appropriate studies, but treatment must begin in a hospital setting.

Contraindications for use include:

• recent myocardial infarction, asymptomatic paroxysmal or unstable ventricular tachycardia (in these diseases, the agent may increase the risk of cardiac arrest and death);

• atrial fibrillation, which is observed over a long period of time (if there is no attempt to restore the sinus rhythm in the patient's anamnesis);

• violations of left ventricular conduction;

• bradycardia (if the patient's heart rate is less than 50 beats / min);

• cardiogenic shock;

• hemodynamically significant valvular heart defects;

• hypersensitivity to the components of the drug.

Also it is important to read an instruction before taking drug, especially if you buy Generic Tambocor online.

The drug is administered orally. To eliminate the effect of food on the absorption of the drug it should be taken on an empty stomach or one hour before a meal. Tablet Tambocor 100 mg can be divided into two equal parts.

The daily dose of the medicine can be different. However, according to the instructions, the amount of drug should not exceed 300 mg per day. In exceptional cases, doctors prescribe 400 mg of this drug per day. When taking it, the tablets should be taken with water. Also, it is undesirable to abruptly stop taking the medication. This can lead to negative consequences. Therefore, you need to gradually reduce the daily dosage before stopping treatment.

Amiodarone and cimetidine can increase the concentration of the active substance (flecainide) in the blood, and carbamazepine, phenothoin, phenobarbital - reduce.

Verapamil and disopyramide may increase some of the negative effects of the drug (eg, inotropic effect).

It is forbidden to combine the drug with other drugs from the category of antiarrhythmics of class I.

Like all anti-arrhythmic drugs, this drug can cause different arrhythmias, including those that it should eliminate. This paradoxical effect should be remembered when using the drug and carefully compare the possible benefits of its use with the possible risk to the patient.

1. If there is an AV block of I or III degree, blockade of the right bundle or a semi-blockade of the left, the use of the drug is possible only if the patient has a pacemaker. Before the beginning of therapy it is necessary to eliminate hyper- or hypocalcemia.

2. This is a very strong remedy, so take it under the supervision of a doctor.

3. During pregnancy and breastfeeding, the drug is prescribed only in exceptional cases and is used with great care. Objective data on the use of Tambocor by pregnant women does not exist, but some clinical studies indicate the toxicity of the drug and its ability to penetrate the placental barrier.

4. The drug should not be given to patients who have a history of congestive heart failure or a reduction in the left ventricular ejection fraction.

5. Increases the threshold of defibrillation.

The most frequent Tambocor side effects of taking medication are:

• visual impairment;

• shortness of breath;

• headaches, dizziness;

• dyspeptic disorders (nausea, constipation);

• increased heart rate, chest pain;

• fatigue, asthenia;

• edema.

Other effects that occur in less than 1% of cases:

• bradycardia, hypo- and hypertension, angina pectoris;

• swelling of the mouth, lips and tongue;

• bronchospasm, pneumonitis, the appearance of pulmonary infiltrates;

• retention of urine outflow, polyuria;

• allergic reactions, itching, dermatitis, alopecia;

• irritation and pain in the eyes, photophobia;

• dry mouth, changes in taste;

• decreased sexual desire, impotence;

• disorders from the nervous system.

The drug should be kept out of the reach of children. Special storage conditions are not required. Shelf life is indicated on the package (usually 2 years). It is possible also to buy Tambocor without prescription in one of safe international pharmacy like Australia online pharmacy.