Poor blood circulation can cause many dangerous diseases. If earlier elderly people suffered from this problem, recently it can be quite often met among young people. To prevent the development of diseases associated with worsening blood circulation, physicians prescribe to their patients various medications that have a vasodilating effect. One such tool is Persantine. For several decades it is very popular.
Persantine is called a drug that has vasodilator, arteriodilating, anti-aggregation and anti-adhesion action. Its use promotes inhibition of the adhesion of platelets, increased blood flow velocity, expansion of coronary vessels and development of collateral circulation in cardiac vessels. This drug normalizes venous outflow, thereby reducing the risk of blood clots, and oxygenates the venous blood. It lowers the brain tone, and also improves placental circulation.
Most of the reviews about Persantine were left by the patients who were assigned to it during pregnancy. Almost all of them praise this drug for its effectiveness, and only a few note the manifestation of such Persantine side effects as a sharp drop in blood pressure and dizziness. Individuals who were prescribed this medication for ischemic heart disease and atherosclerosis also claim that drug Persantine helped them significantly alleviate the condition.
In what kind of disease treatment Persantine is helpful?
Persantine medication is usually assigned in the following cases:
1. Ischemic stroke.
2. Attacks of angina pectoris.
3. Coronary insufficiency of a chronic nature and ischemic heart disease.
4. For the prevention of occlusion of stents and shunts.
5. An acute stage of myocardial infarction.
6. To prevent thromboembolism after surgery in the heart area.
7. In peripheral vascular lesions.
8. Circulatory encephalopathy.
9. Venous and arterial thromboses.
10. Placental insufficiency and preeclampsia in pregnant women.
11. As part of complex therapy in the treatment of malfunctions of microcirculation.
12. Atherosclerosis of the vessels of the legs.
13. DIC-syndrome in children with sepsis and toxicosis.
14. Glomerulonephritis.
15. As an immunomodulator for treatment and prevention of ARVI and influenza.
What should I tell my health care provider before I take Generic Persantine?
It is not allowed to be used in the presence of the following circumstances:
1. Excessive sensitivity to its constituent components.
2. Explicit arterial hypotension.
3. Serious violations of the kidneys.
4. Age to twelve years.
5. Predisposition to bleeding.
6. Acute stage of myocardial infarction.
7. A common atherosclerosis of the arteries of the heart.
8. Unstable angina.
9. Chronic heart failure in the decompensated stage.
10. Liver failure.
11. Diathesis of hemorrhagic type.
12. Serious forms of arrhythmia.
13. Stomach ulcer.
How should I take Persantine?
The dosage of Persantine and the duration of its administration the doctor appoints individually for each individual case. Internally this drug is taken one hour before a meal. To reduce its effect on the mucous membrane of the stomach, you can take the drug with milk.
Dosage information
To prevent thrombosis, patients usually take 300 to 450 milligrams of the drug per day. Persons suffering from coronary insufficiency are prescribed 150-200 milligrams per day.
To prevent thrombosis of the stent and shunts, 50 milligrams of the described drug are administered four times a day with acetylsalicylic acid. The medication should be taken before the operation, and also within seven days after it.
When obliterating vascular diseases of the legs, it is recommended to take 75 grams three times a day. Even if your doctor explained you how to take it you still have to read the instruction especially if you buy Persantine online.
What may interact with Generic Persantine?
The combination of the drug with acetylsalicylic acid, chloramphenicol, tetracycline, oral anticoagulants, cephalosporins and antibiotics of the penicillin series leads to an increase in its antiplatelet effect.
Caffeine, antacids and xanthine derivatives reduce the effectiveness of the described drug. Therefore, during its use, it is recommended to limit the consumption of tea and coffee.
If you combine Persantine with anticholinergic drugs, this can trigger the development of attention and memory impairment in elderly people. This drug has the property of increasing the antihypertensive effect of antihypertensive agents and making the anticholinergic effect of cholinesterase inhibitors less noticeable. It increases the effect of adenosine, and when combined with dobutamine increases the risk of a strong decrease in pressure.
When using the described preparation in the form of a solution for injection, it cannot be combined in one syringe with other medicines.
What should I watch for while taking Persantine?
During the gestation period, women may experience complications such as fetoplacental insufficiency and habitual miscarriage.
The safety of this drug is confirmed by a long history of use and numerous studies.
It is used in the second half of pregnancy to eliminate violations of placental blood flow and improve microcirculation in gestosis, as well as prevent hypoxia of the fetus.
Usually it is prescribed 25 milligrams three times a day for four to six weeks. However, during the first three months of the gestation period, the use of this drug should be avoided.
What side effects may I notice from Persantine?
Application can cause such adverse reactions:
1. Tachycardia or bradycardia.
1. Pain and noise in the head.
2. Lowering blood pressure.
3. Redness of the face.
4. Dyspepsia.
5. Increased bleeding.
6. Thrombocytopenia.
7. The tides.
8. Allergic manifestations.
9. Weakness.
10. Pain in epigastrium, nausea and vomiting.
11. Myalgia.
Where can I keep Persantine?
The drug should be stored in a dry and dark place at an air temperature of no higher than 25 degrees Celsius for two years. It is possible to buy Persantine without prescription in a lot of international pharmacies like Australia online pharmacy.
