A medicinal preparation that is available in the form of tablets. The main active substance is prazosin. The action is reduced to performing the function of the alpha-blocker. The principle is based on blocking the sensitivity of the alpha-adrenergic receptors of the bladder, as well as blocking the alpha-adrenoreceptors of the neck of the bladder and the posterior urethra. This drug is used for prostate adenoma (benign tumor). The result of patients receiving this medication is an improvement in the dynamics of urination and a decrease in the excitation of the prostate gland. Due to this, patients do not experience pain or discomfort.
It does not cause decrease in the minute volume this medicine. Unlike other alpha-adrenoblockers, tablets do not provoke the development of tachycardia.
In what kind of disease treatment Minipress is helpful?
Excellent results medication Minipress showed when it was used in the treatment of patients with prostatic hyperplasia, Raynaud's syndrome. Also, a wide application and high effectiveness of the drug showed in the treatment of spasms of peripheral vessels and pheochromocytoma. In connection with high productivity, the drug received the best reviews in patients with CHF and hypertension.
What should I tell my health care provider before I take Generic Minipress?
The purpose of this medication is not recommended for patients who have such contraindications:
• arterial hypotension;
• increased sensitivity to the active ingredient and additional components of the drug;
• pregnancy and lactation;
• сhildren's age (up to 12 years);
• hyponatremia.
With special care and in markedly reduced doses, it is necessary to use medicine for people suffering from various kidney diseases. Their treatment should be carried out under the strict supervision of the treating doctor. It is forbidden to take medication for patients with allergies to one of the components of the medicine. Extremely important is to read the instruction especially if you buy Generic Minipress online.
How should I take Minipress?
To take this drug patients should internally regardless of food intake.
Dosage information
Begin with a small dose of 0.5-1 mg per day, to take the pill is recommended before bed, after which the patient must necessarily be in bed, because it is possible to intensify the symptoms of the "first-dose phenomenon" - postural hypotension, which can result in a fainting condition .
Particularly expressed is a similar reaction of the human body against the background of the use of various diuretics. In the future, you can increase the dose to 1 mg 3-4 times each day.
Gradually, the dosage increases, to achieve the most maximum hypotensive effect. The manifestation of the effect of the drug in most cases occurs after a few days, but a persistent decrease in blood pressure is observed only after 4-8 weeks.
The maintenance dose should be selected separately for each individual case. It can be from 3 to 20 mg per day. Usually it is 6-15 mg. The total number of tablets is divided into 3-4 doses, setting the most optimal course of treatment. In some patients, the drug is active in a double application.
In monotherapy, one should take into account the possibility of the patient developing early or late tolerance to the drug. In this case, an increase in dosage of about 1 mg is required. Also the combined use of diuretics is practiced.
What may interact with Generic Minipress?
The following interactions are known with other medicines:
• Minipress is absolutely incompatible with "Nifedipine". The effectiveness of the drug is markedly enhanced by such medications as all kinds of sympatholytics, diuretics, and various beta-blockers.
• When combined with beta-adrenoblockers or angiotensin-converting enzyme inhibitors, blockers of small calcium channels significantly increase the risk of development of pronounced arterial hypotension.
• The vasodilating effect of calcium channel blockers and alpha-blockers can be either synergistic or additive.
• With the parallel administration of the drug along with "Verapamil", a pronounced arterial hypotension is observed, which is in part due to the pharmacokinetic effect of the drugs: the increased maximum concentration, and the total concentration of drug Minipress.
• "Indomethacin" can significantly reduce the effectiveness of the medication.
• Minipress drug usually contributes to the rapid and significant increase in the amount of digoxin that is contained in the blood plasma. In addition, it can change the antihypertensive effect of "Clonidine."
What should I watch for while taking Minipress?
The manufacturer recommends to use the drug in prostate adenoma in the first dose not more than 0.5 mg. usually this is done before bedtime. It is important that the patient is in bed for 6 to 8 hours after taking the drug. Especially bright such a reaction can be manifested with the previous intake of diuretics. Given such a feature for elderly patients or suffering from frequent changes in blood pressure, it is important to pay particular attention to the choice of dosage. In connection with such risks, the dosage and frequency of taking the drug may be prescribed only by the directly treating specialist.
What side effects may I notice from Generic Minipress?
In some cases are possible the following Minipress side effects:
1. The so-called "first-dose phenomenon".
2. Sensation of dryness of the oral mucosa.
3. Prolonged headache.
4. There is dizziness.
5. Increased fatigue, general weakness.
6. Manifestation of chronic insomnia.
7. Nausea with vomiting;
8. Constipation.
9. Diarrhea.
10. Greatly increased heart rate.
11. Significant deterioration of vision.
12. Notable emotional disorders.
13. Development of the Vertigo.
14. Unreasonable anxiety.
15. Occurrence of hallucinations.
16. Paresthesia of the upper and lower extremities occurs.
17. Depressive state.
18. Pain sensations of an anginous character.
19. Occurrence of dyspnea.
20. Education of edema on the legs.
21. Intensive development of arterial hypotension.
22. Symptoms of orthostatic collapse.
23. Enough urination.
24. There is a noise in the ears.
25. Darkening in the eyes.
26. Signs of hyperemia of the cornea of the eye.
27. Itching feels severe, skin can become covered with a rash.
28. The presence of the upper respiratory tract.
29. The appearance of hyperthermia.
30. Symptoms of priapism.
31. Explicitly expressed alopecia.
32. Signs of arthralgia.
In some patients, other side effects are possible, which depend on the individual characteristics of their body. As a rule, they disappear after a while after stopping the medication. In addition, their manifestation is most often observed in elderly patients, so they need to more carefully choose the dosing of this medication.
Where can I keep Minipress?
The drug is recommended to store in a place that is reliably protected from penetration of direct sunlight, at a moderate temperature of air. The medicine should be inaccessible to young children. Minipress is usable for three years from the time it was manufactured. You can also buy Minipress without prescription in Canada online pharmacy.
