This drug refers to cardiac glycosides. It has the following useful properties: inotropic, moderately diuretic and vasodilating.
Lanoxin is capable of:
• increase systolic and stroke volumes of the heart;
• to raise the refractory period;
• reduce antivenovticular conductivity;
• reduce the frequency of heart contractions.
With stagnant phenomena of cardiovascular insufficiency, it has a vasodilating effect. Has a mild diuretic effect, reduces shortness of breath and swelling.
The drug is produced by GlaxoSmithKline Plc, a recognized world leader in the manufacture of prescription drugs.
After ingestion, the drug is immediately absorbed from the stomach-intestine. After 1 hour in the blood, you can observe the required concentration of the drug. Bioavailability of the drug is 60-70%. The maximum concentration is achieved in an hour and a half after the administration of the drug.
The half-life will depend on the age of the patient and the functionality of the kidneys. In young people this period is 36 hours, in the elderly it is 68 hours. In the composition of 80%, the drug is eliminated by the kidneys in unchanged form.
In what kind of disease treatment Lanoxin is helpful?
• Chronic cardiovascular failure;
• Tachyarrhythmia (supraventricular paroxysmal) - with arrhythmia of atrial fibrillation, atrial fibrillation and paroxysmal tachycardia.
What should I tell my health care provider before I take Generic Lanoxin?
The dosage of the drug is selected by the doctor according to individual indications. Pills are recommended to be swallowed whole, washed down with a small amount of water. Food intake does not affect the effectiveness of the drug.
Dosage information
A single dose of Lanoxin for adults - 0.00025g or 1 tablet of 0.25 mg. At the beginning of therapy, the drug is consumed up to 4-5 times a day at regular intervals. The dose per day is 1-1.25 mg. On the second day of treating, the same dose is prescribed, but up to 1-3 times a day.
The therapeutic effect is evaluated by electrocardiography, urination and respiratory function. Based on the indications, the dosage can be increased or decreased. As soon as the therapeutic effect is achieved, the drug is prescribed according to this scheme: 0,5-0,25-0,125 mg. The daily dose for adults is 1.5 mg or 0.0015 g.
• In heart failure, Lanoxin is started taking with a maintenance dose (about 0,125-0,25 mg per day).
• In cardiac arrhythmia, in the initial stage of therapy, higher doses are used - 0.375-0.5 mg per day.
• In sinus rhythm, the drug is not used in large doses (up to 0.25 mg / day).
• Approximate daily dosage in pediatrics is 0.05-0.08 mg per 1 kg of the child's body weight.
What may interact with Generic Lanoxin?
Inform your doctor about taking the following drugs, as their combination may provoke a bad reaction of the body. To the list of drugs belong: diuretics, as well as insulin, glucocorticosteroids, preparations of calcium salts and sympathomimetics, acids, tannins, metal salts and alkalis, erythromycin, quinidine, verapil and amiodarone, verapamil, amphotericin B, intravenously calcium preparations for those patients who take cardiac glycosides and others.
What should I watch for while taking Lanoxin?
During pregnancy, the drug can penetrate the hematoplacental barrier. In the fetal blood, the content of the drug will be of the same concentration as that of the future mother. The drug is prescribed only with the advantage of the benefit from its administration over possible threats to the unborn child.
In breast milk drug Lanoxin gets slightly. But with lactation it is necessary to monitor the child's heart rate. In case of renal failure, the dose of the drug should be reduced (up to 25-75% of the daily dose - for glomerular filtration less than 50 ml / min and for the usual dose of 10-25% - for glomerular filtration not more than 10 ml / min).
During the reception, regular monitoring of the heart with the help of electrocardiography and determination of electrolyte balance in the blood are necessary.
What side effects may I notice from Lanoxin?
Manufacturers warns about possible Lanoxin side effects:
• change in the heart rate.
• nausea, poor appetite, vomiting, diarrhea.
• weakness, fatigue, headaches, apathy, depression, fear of light, diplopia, psychosis, flies before the eyes.
• gynecomastia (in case of too long consumption).
• petechiae and thrombocytopenia.
• urticaria and itching.
Symptoms of overdose occur when glycosidic intoxication. It is characterized by:
• sinus bradycardia;
• ventricular extrasystoles of the type of bigeminy;
• atrial tachycardia;
• ventricular fibrillation;
• retardation of antrioventricular conduction;
• blockade antrioventricular.
There may also be non-cardiac signs of an overdose: dyspepsia (nausea, diarrhea or vomiting, anorexia), memory impairment, muscle weakness, drowsiness, headache, psychosis, erectile dysfunction, euphoria, gynecomastia, anxiety, flies, blurred vision, scotoma, macro and microposs.
Where can I keep Lanoxin?
The medicine should be kept in a dry, darkened and inaccessible place for children and pets. Shelf life - up to 3 years. The drug is released on prescription but it is possible to buy Lanoxin without prescription in Portugal online pharmacy.
