The drug is an antiviral drug that is used systematically. Upon receiving this drug internally its active substance Famciclovir at a high speed is transformed into Penciclovir which has activity against human herpes viruses including herpes zoster, genital and labial herpes simplex virus and cytomegalovirus and Epstein-Barr virus.
Penciclovir penetrates into cells that are infected with a virus where the action of thymidine kinase (enzyme) at a high speed is transformed into monophosphate and it involving cell enzymes is transformed into the triphosphate. In cells infected with viruses, penciclovir triphosphate contains more than 12 hours there suppressing replication of viral DNA molecule. In uninfected cells the substance concentration of Penciclovir triphosphate is minimal. Therefore, therapeutic drug doses have no effect on uninfected cells. It is also active with respect to the newly discovered strains of the virus Herpes simplex in which is modified enzyme DNA polymerase.
In what kind of disease treatment Famvir is helpful?
It is used when caused by a virus:
Herpes zoster infections, inclusive and with ophthalmic postherpetic neuralgia;
Herpes simplex infection: primary infection, exacerbation of chronic infection, suppression of recurrent infection (for the purpose of prevention of relapse);
Varicella zoster, Herpes simplex infections in patients who have a reduced immune system.
What should I tell my health care provider before I take Generic Famvir?
It is not advisable using of the drug by people who have an intolerance of its components. There are no reviews on the use of Famvir by children under the age of 18 years so they can be assigned the drug only when the benefit from taking it more than the potential risk. Also it is necessary to refuse taking of the medicine to women who are breastfeeding and women who are expecting a child. If you prefer to buy Famvir online then remember to read the instruction which you can find in the package.
How should I take Famvir?
The tablets should be taken by mouth, regardless of the meal. They do not need to be chewed. The best result of the drug will be able to show in that case if treatment was initiated maximum earlier before the manifestation of the first symptoms of illness (when in shingles and herpes occurs tingling and itching).
Dosage information
If there is a herpes zoster then a person with normal immunity should take three times a day 0,5 grams of the drug. The course of treatment is one week. Exactly the same pattern should be followed for the ophthalmic manifestations. This mode allows you to reduce the neurological manifestations of the disease.
People with poor immune systems with herpes zoster should take 0,5 grams / 3 times. In case of genital herpes (primary) people with normal immune systems are encouraged to nominate 0.26 grams also 3 times. This course should continue for five days. At relapse - twice a day by 1 gram for 2 days or 0,125 grams / twice for five days.
In relapsed herpes labialis in the case of normal immunity treatment is carried out in one step - 1, 5 grams or twice daily at 0.75 grams. If the immune system is reduced then for the treatment of herpes labialis and genital patients need to take the drug three times a day 0,5 grams for 7 days.
You should know that the method of transmitting of genital herpes is sexual intimacy. When herpes is in the acute stage, it significantly increases the risk of infection. If a person has violated kidneys then Famvir is assigned in a lesser dosage. People in old age in which kidney's okay do no need to adjust the dose.
What may interact with Generic Famvir?
Under the action of probenecid increases the level metabolite penciclovir in blood plasma. There are no other significant interactions.
What should I watch for while taking Famvir?
If there are clinical manifestations of genital herpes (a disease that is transmitted sexually) patients should avoid sexual intercourse, even if antiviral treatment has already started.
What side effects may I notice from Generic Famvir?
Reviews of Famvir suggest that its use may cause side effects in the form of:
Confusion;
Itching;
Vomiting, nausea;
Jaundice;
Headache;
Hallucinations;
There may be a Stevens-Johnson syndrome;
Drowsiness;
Vertigo;
Rash;
Erythema multiforme;
Allergic reactions, diarrhea, dizziness;
In elderly patients it is confusion, hallucinations;
In the case of lowered immunity - abdominal pain, fever and occasionally - granulocytopenia and thrombocytopenia.
In general, according to a clinical study is established a good tolerability of Famvir including patients whose immune system is lowered. With an overdose of Famvir in the dosage of 10.5 grams did not arise manifestations of any symptoms. If you do not adjust the dose in chronic renal failure, it can cause acute renal failure. In hemodialysis from blood is derived the active ingredient of the drug.
Where can I keep Famvir?
Keep the medication in a dry place at a room temperature. Do not let your kids play with it cause it may be dangerous.