Aralen (its operating agent Chloroquine Phosphate) is an antimalarial remedy.
In what kind of disease treatment, Aralen is helpful?
Therapy of acute attacks of malaria provoked by sensitive to a preparation plasmodium malaria prevention in people visiting endemic areas; cure of extra-intestinal amebiasis in a combination therapy of rheumatoid arthritis, systemic lupus erythematosus, photodermatosis, individual events of late cutaneous porphyria.
What should I discuss with my healthcare provider before taking Aralen?
Alterations in the retina and or visual field of various origins
Personal intolerance to the ingredients of the preparation
Abnormal liver and kidney function
Pronounced lesions of the heart muscle (with arrhythmia)
Ailments of blood, nervous system, psoriasis
Porphyrinuria
With care prescribe Aralen to sick with G6PD, chronic alcoholism.
How should I take Aralen?
You will need a bottle of water. Place the pill on the tongue. The lips press to the neck of the bottle. Take a sip and the tablet together with water float away in the right direction. The density of the tablets is much higher the density of water, so they are often not "washed away" and get stuck in the mouth. However, using this technique, you will easily wash away the tablet directly into the pharynx towards the esophagus. Look for the remedy in your local Italy drugstores or purchase Aralen online at the lowest price.
Aralen dosage information
Malaria prevention in grownups: 500 mg week, always in one and the same day of the week. Receiving of Aralen starts in 1-2 weeks prior to the arrival in the endemic area and continue for 4-6weeks after the departure from there. Kids: 7.6 mg kg week.
During an episode of malaria for grownups: in the 1st intake appoint 1 g; after 6-8 hr 500 mg; on the 2nd and 3rd day 500 mg. Diurnal dose must be taken at 1 reception. For kids designate initial dose of 16 mg kg in 1 reception; then after 6h 7.6 mg kg. On the 2nd and 3rd days of reception: 7.6 mg kg day. The length of the course is 3 days.
With extra-intestinal amebiasis for mature people prescribe 1 g day in 2 receptions for 2 days, then 500 mg day in 1 reception for 2-3 weeks. Aralen is advised to take in combination with preparations acting on the intestinal form of amoebas. For kids prescribe 16 mg kg day in 1 intake for 2-3 weeks. The maximum daily amount of the preparation: 500 mg day.
In need of carrying immunization against typhoid with peroral preparations reception of Aralen starts in 3 days after the end of the immunization.
In rheumatoid arthritis, for mature people is advised to take 250 mg day. The therapeutic effect appears as a rule on the 4th week of the course. After remission or if has been achieved the maximum effect, dosage of Aralen must be reduced.
In SLE for mature people prescribe 250 mg day.
What may interact with?
Antacids violate absorption; cimetidine increases the concentration in plasma. Combining with other antimalarial agents can provide antagonistic effect. Is incompatible with preparations of gold, penicillamine, phenylbutazone, cytostatics, levamisole (due to neurotoxicity and strengthen the probability of skin reactions). When combined with glucocorticoid enhances the hazard of cardiomyopathy; with MAO suppressors — toxicity of ethanol; with cardiac glycosides — glycoside intoxication.
What should I watch for while taking Aralen?
Clinicians believe that a variety of parasites in the period of carrying a baby is certainly not too pleasant, but still the risk is not large enough to start using so strong preparations, like Aralen. Therefore, its usage must be strictly justified and therapy is carried out only under constant medical attention.
We encourage those individuals who are planning to visit countries with hot climates, to contact the infectious diseases doctor beforehand for advice and tips on prophylaxis of malaria. After returning home you must contact the attending physician and inform about your arrival from tropical countries. The physician may prescribe a further reception of the preparation. In individual cases malaria can occur in more serotinal terms, even with the use of antimalarial drugs. Therefore, in case of malaise, accompanied by temperature increase, seek medical advice immediately. Within 2 years after the return home at any malaise do not forget to remind your physician that treats you, that you were in the tropics.
Aralen side effects
On the CNS and auditory organs: headache, vertigo, agitation, neuropathy, myopathy and tinnitus. In the event of muscle weakness, therapy must be stopped at once. The preparation can provoke exacerbation of psoriasis and porphyria, hearing loss (especially in predisposed people).
It is necessary to consider the probability of intolerance to Aralen in sick with hypersensitivity to 4-aminoquinoline derivative (most frequently in kids). Chronic reception of Aralen at a dose of 150 mg day and more requires a systematic control of tendon reflexes, peripheral blood, as well as the inspection at an ophthalmologist at least 1 time in 6 months.
On eyesight: blurred vision, disturbances of accommodation, "annular" and or temporal scotoma, invertible keratopathy; retinopathy. Lowering sharpness of vision is possible upon receipt of small doses of the preparation, which must be considered in sick involved in potentially hazardous activities that require increased attention and rapid mental and motor responses.
On GI: anorexia, nausea, vomiting, diarrhea, stomach cramping.
On the cardiovascular system: seldom hypertension; at long reception of large doses cardiomyopathy.
Expiration date, denoted on the packaging of the preparation, would be accurate only if you have kept the preparation due to the rules dictated by the manufacturer. Otherwise, at best, the drug medicine would simply lose its properties, and in the worst —toxic components resulting from chemical reactions would generate. So do what you are asked in the instructions, it's for your own safety. Your physician must provide you with this data or you could get it with the tablets if you buy Aralen online. Store the medicine at a temperature no higher than indicated in the annotation (15-22°C). Once opened is possible evaporation of Aralen tablets, absorption by them volatile substances or reaction with oxygen (oxidation). Therefore keep the tablets in the original sealed packaging.
