This is a drug related to bone resorption inhibiting agents that inhibits the activity of osteoclasts. The active substance refers to highly active biophosphonates. The drug produces a stopping of bone destruction during periods of retinoic therapy, with a change in the hormonal background, with oncological pathologies.
The drug is available in 2 forms for ingestion of 2.5 mg for daily intake and 150 mg for a monthly dose, as well as in the form for intravenous administration at a dose of 3 mg once every 3 months. It is believed that this drug is more effective with a monthly intake, rather than with a more infrequent introduction.
Ibandronae Sodium is used to treat postmenopausal osteoporosis in order to prevent fractures. This medicine receives positive feedback from people who have been taking treatment therapy with it.
The drug belongs to the group of biophosphonates and is considered to be a nitrogen-containing compound. It can uniquely suppress the active action of osteoclasts without affecting their number. Also, main substance lowers bone resorption.
Carcinogenic, genotoxic effect of medication is not noted. The drug makes stop bone destruction during retinoid therapy, with changes in the hormonal background, with oncological pathologies.
In what kind of disease treatment Boniva is helpful?
The drug Boniva is indicated in the presence of osteoporosis in women during menopause. Use the drug to reduce the brittleness of the bones in this state.
Receiving a drug by women during menopause leads to normalization of bone tissue up to reproductive age, resulting in:
• mass of bone tissue increases;
• bone collagen degradation rates are reduced;
• increases mineral bone density;
• the frequency of fractures decreases.
What should I tell my health care provider before I take Generic Boniva?
Contraindications include:
sensitivity to the components of the drug;
hypocalcemia;
achalations of the esophagus
stricture of the esophagus;
pregnancy;
lactation period;
the lack of opportunity is in the upright position of pcint, within an hour from the time of taking the tablet;
age up to 18 years.
How should I take Boniva?
A pill should be taken internally and washed down with a liquid (but not grapefruit juice). Tablets are taken in holistic form, drinking water, while in the vertical position (sitting, standing). The patient is not allowed to lie down for 60 minutes after taking the pill. Search on online pharmacy portugal
Dosage information
It is recommended that you take a medication of 150 mg only once a month, preferably on the same day of each month. The drug should be taken 60 minutes before the start of the first meal, liquid (except water) on that day or other medications. It is forbidden to take a preparation in an amount greater than 150 mg per week.
When skipping the next monthly reception, you should take a pill as soon as the opportunity is presented, and then take the next according to the schedule set by the attending physician. If the next appointment is overdue for more than 23 days, you should wait for the schedule of the day of admission and then stick to the schedule. Under no circumstances should be allowed for one week of taking 2 tablets of 150 mg. In liver pathologies, elderly patients, in case of kidney diseases with a QC of ≥30 ml / min, no specific dosage adjustment with standard correction is required. About more detailed instruction you can ask your physician but if you buy Generic Boniva online then be sure to read the instruction which you can find in the packaging.
What may interact with Generic Boniva?
Interaction with other medicines:
Group of drugs
Possible interaction with Boniva
Calcium-containing drugs
Infringement of Ibandronae Sodium suction
NSAIDs
Increased irritation of the gastrointestinal tract
Injection solution of ranitidine
Enhances the bioavailability of the drug
Iron Preparations
Reduce absorption of Bonviva tablets, alter biotransformation of the drug
Aluminum containing preparations, means with magnesium
Infringement of suction of main substance
What should I watch for while taking Boniva?
In the course of treatment with this drug, you must additionally administer the drugs with calcium and vitamin D.
A doctor who cares for a patient is required to conduct a series of examinations to determine the presence of symptoms of damage to the esophagus.
A number of recent studies have described cases of osteonecrosis of the jaw in patients taking bisphosphonates. The pathogenesis of this complication is not clear, but the risk factor is probably the preceding treatment at the dentist.
What side effects may I notice from Boniva?
gastritis;
pain in the head;
nausea;
esophagitis;
myalgias;
dyspepsia;
arthralgia;
diarrhea;
skin rash;
muscle spasm;
back pain;
dizziness;
nasopharyngitis;
urticaria;
thrombophlebitis;
flu-like syndrome;
uveitis;
osteoarthritis;
esophagitis;
bronchitis;
angioneurotic edema;
duodenitis;
increase in blood pressure;
hypercholesterolemia;
swelling of the face;
phlebitis;
scleritis;
depression;
osteonecrosis of the jaw;
pain in the bones;
rigidity of muscles;
local inflammation;
insomnia;
cystitis;
gastroesophageal reflux disease;
atypical fractures (afferent, diaphyseal);
fatigue.
Overdose:
Excessive therapeutic dose is accompanied by:
- dyspepsia;
- heartburn;
- ulceration of the upper sections of the gastrointestinal tract;
- esophagitis.
Relative antidotes include milk, antacids. The procedure of artificial vomiting is contraindicated because of an increased risk of damage to the esophageal mucosa.
Where can I keep Boniva?
The drug should be stored out of reach of children at a temperature not exceeding 25 ° C. Shelf life of medication is 2 years. Do not use it after the expiration date. Do not take pills if the packaging is damaged (it can happens in a high humidity place). You can buy Boniva without prescription in every international pharmacy, for example, in Spain online pharmacy.
