Vasotec belongs to a group of synthetic drugs designed to lower blood pressure. It has long been known for hypertensive patients. This medicine requires careful use. Therefore, it cannot be taken without consulting a doctor. It is also important to read the instructions for use especially if you buy Generic Vasotec online. It has an antihypertensive effect (gradually lowers blood pressure). Other medicinal properties of the drug include:
•dilates blood vessels,
•reduces the vascular resistance at the periphery,
•relieves stress on the myocardium,
•lowers the pressure in the area of the small circle of blood circulation,
•increases the ability to withstand physical activity,
•reduces deformities in the left ventricle,
•improves the picture of glomerular hemodynamics in the kidneys (preventing diabetic nephropathy).
The drug promotes the expansion of the arteries to a greater extent than the veins, without a reflex jump in heart rate readings. The maximum result is formed after a lapse of 6-8 hours from the time of admission and is kept for 24 hours.
About 60% of the amount of the dose taken is rapidly absorbed from the gastrointestinal tract. Metabolism of the drug occurs in the liver. From the body it is excreted in the main body by the kidneys, as well as by the intestine.
In what kind of disease treatment Vasotec is helpful?
According to the instructions, Generic Vasotec is indicated in:
•arterial hypertension at any stage (including renovascular),
•left ventricular dysfunction,
•diabetic nephropathy,
•heart failure in chronic form (as an element of complex treatment).
What should I tell my health care provider before I take Generic Vasotec?
The list of contraindications includes:
•angioedema due to the use of ACE inhibitors,
•Quincke's edema of hereditary nature,
•porphyria,
•disruption of kidney function and stenosis of their arteries,
•azotemia,
•hyperkalemia,
•after a kidney transplant,
•the state of pregnancy and feeding,
•children under 18 years of age (no safety or performance data),
•hypersensitivity to enalapril and other ACE inhibitors.
Conditions in which increased caution is necessary:
•systemic diseases of connective tissue,
•ischemic disease,
•cerebrovascular diseases,
•renal and hepatic insufficiency,
•hemodialysis,
•diabetes mellitus (due to possible hyperkalemia),
•compliance with a salt-free diet,
•parallel treatment with immunosuppressants and saluretic drugs,
•old age (from 65 years).
How should I take Vasotec?
Drug Vasotec is administered orally regardless of food. The drug is used in monotherapy, as well as in combination with other antihypertensive medications. If arterial pressure is difficult to support just with Vasotec medication, then diuretic therapy is attached.
Dosage information
The primary Vasotec dose is determined depending on the level of the disease. Usually it is equal to a one-time intake of 2.5 to 5 mg per day. The intake of the initial dose should be under medical supervision for 2-3 hours, until the pressure stabilizes. If necessary, a single dose increases to 20 mg and can be divided into two doses per day. The usual maintenance dosage goes through two to three weeks. The maximum amount of a drug is 40 mg per day (with its normal tolerability). When the dosage is prescribed, the nature of the disease is taken into account:
• Renovascular hypertension requires an initial daily dose of 2.5-5 mg, a maximum of 20 mg;
• in simultaneous treatment with diuretics, 2.5 mg are initially given;
• if there is chronic heart failure, a single initial dose is prescribed 2.5 mg, then it is raised from 2.5 to 5 mg in 3-4 days, depending on the clinical response and to the maximum when controlling pressure, but not more than 40 mg per day ;
• in a low systolic pressure (below 110 mm Hg), the treatment regimen starts from 1.25 mg per day. The dose is selected from 2 to 4 weeks. On average, the maintenance amount per day is 5-20 mg;
• elderly patients are prescribed a primary dose of 1.25 mg, this is associated with a more pronounced hypotensive effect and an extended duration of the drug due to a reduction in the rate of its elimination.
What may interact with Generic Vasotec?
It is important to know about the combination of Vasotec with other drugs, as indicated by the instruction:
1. The combination with anti-inflammatory non-steroidal drugs can reduce the hypotensive effect. The same result occurs when eating food with sodium chloride in large quantities.
2. Adding to the treatment of potassium-sparing diuretics (amyloid, spironolactone) is dangerous hyperkalemia.
3. The combination with lithium salts is fraught with delayed lithium removal.
4. The effectiveness of the drug may decrease from the simultaneous administration of analgesic and antipyretic agents.
5. It reduces the effect of drugs with theophylline.
6. The hypotensive effect of the drug is enhanced by diuretics, nitrates, beta-adrenoblockers, prazosin, methyldop, and hydralazine.
7. Hematotoxicity increases from immunosuppressants, cytostatics, and allopurinol.
What should I watch for while taking Vasotec?
Before treatment and during the reception it is necessary to resort to periodic monitoring of blood pressure, hemoglobin, urea and other indicators of blood, protein in the urine.
What side effects may I notice from Generic Vasotec?
The possible negative consequences of taking Vasotec are:
•high drop in blood pressure,
•retrosternal pain,
•myocardial infarction,
•orthostatic collapse,
•angina pectoris,
•arrhythmia,
•dizziness with headache,
•insomnia,
•confused consciousness,
•weakness,
•anxiety,
•depression,
•excessive fatigue,
•dyspeptic disorders,
•dry cough,
•bronchospasm,
•intestinal obstruction,
•shortness of breath,
•itching and skin rash,
•stomatitis,
•disruption of the kidneys,
•tides,
•decreased libido.
Where can I keep Vasotec?
The instruction states that the packages with the medicine should be stored in conditions protected from moisture in a temperature of 15 to 25 ° C. Children should not have access to a medicine. The expiration date is three years. After this time, the tool cannot be used. There is a possibility to buy Vasotec without prescription in Greece online pharmacy.
