It belongs to the group of azodilating agents. The active substance is nitroglycerin. This is a common name for medical products that contain glycerol trinitrate. The drug has the following useful properties:
• Dilates the blood vessels (cardiac, coronary, arteries of the brain);
• It is able to relax the smooth musculature of the stomach and intestines (of the bronchi, gall bladder, urinary tract, esophagus);
• Relieves the smooth muscles of the biliary tract and other organs;
• Reduces the venous return of blood to the heart;
• Reduces the infarction of foci of ischemic lesions;
• Improves the contractile function of the heart muscle and the metabolism in the myocardium;
• Oxygen saturation of the myocardium, susceptible to ischemia,
• Increased cardiac output,
• Increase the tolerance of physical activity,
• Possessing spasmolytic effect, it exerts a central inhibitory effect on the sympathetic tone of the vessels, while inhibiting the component of the formation of pain syndrome.
In what kind of disease treatment Nitrostat is helpful?
Nitrostat is used:
• To relieve angina attacks;
• For dyskinesia of bile ducts;
• When the central artery of the retina is clogged;
• In MI and left ventricular failure.
What should I tell my health care provider before I take Generic Nitrostat?
The drug Nitrostat is contraindicated in the following cases:
• Brain hemorrhage;
• Intracranial pressure is higher than normal;
• Hypersensitivity to the constituent elements of the drug;
• Low blood pressure;
• Closed-angle form of glaucoma (high intraocular pressure).
In the open-angle form of glaucoma, preparations with this main substance are not contraindicated.
With extreme caution, the drug should be taken in any form when:
• Hemorrhagic stroke;
• Intracranial hypertension;
• Acute MI with low pressure;
• Severe anemia;
• Thyrotoxicosis;
• Arterial hypotension with low systolic blood pressure;
• Severe renal failure;
• Liver failure;
• Pregnancy and lactation;
• At the age of 18 years (safety of use not established).
How should I take Nitrostat?
A half of a tablet or the whole pill is put under tongue and hold in a mouth before its dissolution. It is possible to accelerate the positive effect if to crack with teeth a pill.
Dosage information
The frequency and duration of the drug in any form depends on the intensity and frequency of angina attacks, as well as the tolerability and efficacy of the drug. Usually, after stopping the heart attack, doctors switch it to longer-lasting medications.
In the practice of an ambulance, in case of a heart attack or heart failure in the acute phase, doctors prescribe nitroglycerin intravenously. Before the introduction of a drug into the vein, 1-2 tablets are taken first under the tongue, repeating the intake every 15 minutes.
Tablets that are designed to prevent angina pectoris should be taken orally and washed down with water before eating. In no serious cases are taken 0,0026-0,0064 g 3 times a day. And in more serious cases it is 0,0064-0,01 g 3 times a day.
It should be taken into account that a continuous long-term intake of Nitrostat in any form can provoke the development of tolerance (addiction) to the drug. This can lead to a constant increase in the dose or number of doses. If you don’t know an exact dosage then you should call your doctor and read an instruction that you can find in the package if you buy Generic Nitrostat online.
What may interact with Generic Nitrostat?
In administration patients should be very careful with cardiac tamponade, craniocerebral trauma, constrictive pericarditis, hypovolemia, toxic pulmonary edema and atherosclerosis.
• In case of complex application of Nitrostat with beta-blockers, vasodilators, sildenafil, ACE inhibitors, hypotensive drugs, procainamide, MAO inhibitors, tricyclic antidepressants, PDE and ethanol inhibitors, hypotensive effect may increase;
• combined use with dihydroergotamine can increase the concentration of the latter in the blood, as well as raise blood pressure;
• Nitrostat and heparin together reduce the effectiveness of the latter, and after drug withdrawal, it may be necessary to reduce the dose of heparin.
What should I watch for while taking Nitrostat?
Since patients often have to use nitrates for a long time, the effectiveness of therapy should be monitored continuously, regulating the dosage (possibly for several days), as well as the abolition of these drugs, replacing them with antianginal drugs of other groups.
What side effects may I notice from Generic Nitrostat?
When using the drug, the following Nitrostat side effects may occur:
• Headache;
• Dizziness;
• Anxiety and psychotic reactions;
• Retardation;
• Nausea and vomiting;
• Lowering of blood pressure (more often in the vertical position of the body);
• There may be allergies in the form of rashes, dermatitis or skin flushing;
• A sharp drop in blood pressure when changing from horizontal to vertical position.
It is better to avoid getting the solution on the skin, as the drug can be absorbed and cause a headache.
If an overdose of the medicine occurs, it can be detected by the symptoms:
• Headache and dizziness,
• Reducing blood pressure,
• Reflex tachycardia,
• Redness of the face,
• Increased drowsiness,
• Diarrhea and vomiting,
• Feeling of heat.
The intake of extremely high doses (above 20 mg per kg) is dangerous:
• An increased amount of methaemoglobin,
• Tachypnea and dyspnea,
• Cyanosis,
• Orthostatic collapse.
Where can I keep Nitrostat?
It should be kept in a dark and cool place (temperature under 75 F). The product is explosive and flammable. It is unacceptable to store and use it near fire and during smoking. Do not dispose of an empty container into a fire. Children should be denied access to the storage place. The drug has a three-year shelf life. You can also buy Nitrostat without prescription in international pharmacies like Denmark online pharmacy.
