It is a remedy that stimulates hormonal activity. This substance itself is not a hormone, but, according to scientists, it binds to receptors that react to estrogen in the pituitary and hypothalamus. In low and medium doses, this stimulates the production of follicle stimulating and luteinizing hormones, which are united in the group "gonadotropins." Such stimulation can help to correct the processes of ovulation in women and the formation of sperm in men.
Clomid deserved good reviews from patients who took it.
The effect of the drug is expressed in the special binding of the ovaries and the pituitary gland by means of estrogen receptors. Depending on the amount of estrogen in the body, it can have an estrogenic effect in moderation or an anti-estrogenic effect. In a small amount increases the secretion of gonadotropins, in a large lowers, stimulates ovulation.
The active ingredient is well absorbed from the gastrointestinal tract after the time has elapsed after using it inside the drug. The clomiphene component metabolizes in the patient's liver. At the same time, it is prone to intestinal hepatic recirculation. Drug is withdrawn together with bile. The withdrawal period can be from 5 to 7 days.
Of course, not in all cases, such stimulation leads to pregnancy. But the success statistics of this method are very encouraging. Some women even think about whether to take medicine on their own. To do this, of course, absolutely forbidden you can break your own health. Even if conception occurs, you cannot competently protect yourself from the risks that threaten such a pregnancy.
In what kind of disease treatment Clomid is helpful?
Direct indications for the appointment and use can be such diseases and conditions:
Polycystic ovaries (for example, in the Stein-Levental syndrome);
Amenorrhea or oligomenorrhea (absence or scarcity of menstrual bleeding);
Functional uterine bleeding;
The scanty amount of sperm in men;
Androgen insufficiency;
What should I tell my health care provider before I take Generic Clomid?
Contraindications include:
insufficiency: renal, hepatic;
dysfunction of the adrenal gland, thyroid gland;
endometriosis;
sensitivity to the substances of the drug;
pregnancy;
lactation;
ovarian cyst (except for polycystic ovaries);
lactose intolerance;
visual impairment;
swelling, hypofunction of the pituitary gland;
functional failure of the ovaries due to hyperprolactinemia.
How should I take Clomid?
These pills are taken orally. Usually the reception of tablets begins on the fifth day of the menstrual cycle.
Dosage information
If the cycle of menstruation is not broken, then therapy is recommended to begin on the 5th day of the cycle. With early ovulation and the duration of the follicular phase is less than 12 days, therapy is started on day 3 of the cycle. If you have amenorrhea, you can start treatment on any day.
A specific scheme has been developed, adhering to which the therapy will be more effective. Following this scheme, you must take 50 mg of the drug for 5 consecutive days. At this time, it is obligatory to conduct clinical and laboratory studies, due to which the ovarian response is determined. If the effect of the drug has been beneficial, then the expected ovulation occurs between 11 and 15 days.
What may interact with Generic Clomid?
Clomid is permissible for use simultaneously with any of the gonadotropic hormonal drugs.
What should I watch for while taking Clomid?
Before you start taking the drug, you need to examine the function of the liver, as well as a detailed gynecological examination. Treatment is started with gonadotropin in urine in normal or low borderline and also at normal indicators of a status of ovaries at a palpation, functionality of adrenals and a thyroid gland.
Taking the drug increases the possibility of a multiple pregnancy. Considering the fact that the drug can cause a visual impairment, care should be taken to manage the vehicles, as well as to engage in hazardous activities.
If the examination determines the fact that the egg is not maturing in the patient, it is necessary to determine the possible causal problems of these problems and to treat them, only after that is prescribed drug Clomid. Since the time of taking the drug is difficult to accurately track down the time of ovulation, it is necessary to constantly monitor the activity of the ovaries. Also, the lack of a yellow body can be determined. This is the reason after conception to appoint patient progesterone as a prophylaxis. In case of an increase in the ovaries or cystic transformations of these organs, after returning to normal, the dosage of the drug should be reviewed and the optimal course of Clomid treatment determined.
What side effects may I notice from Generic Clomid?
a feeling of nausea;
headache;
drowsiness;
vomiting;
frequent urination;
dryness of the vagina;
compaction of mammary glands;
impaired vision;
rare allergic reactions in the form of hives or rashes;
dizziness.
During overdose of the drug can be observed nausea, vomiting, flow of blood to the face, a breakdown in visual function (the presence of bright spots, a drop in clarity), swelling of the ovaries, pain in the pelvis and abdomen. The removal of symptoms is carried out by measures which action is aimed at removing the active substance from the body. It is necessary to conduct general therapy. There is no confirmation of the withdrawal of clomiphene by dialysis.
Where can I keep Clomid?
The drug should be stored in a place limited to children at a temperature of 15 to 25 degrees Celsius. The drug is suitable for 5 years from the date of manufacture. Do not use the medication at the end of the expiration date. You can buy Clomid over the counter in United Kingdom online pharmacy.
