It is an ACE inhibitor. It restores the elasticity lost by large arterial vessels, reduces the pressure in the capillaries of pulmonary, with prolonged use reduces the severity of interstitial fibrosis and myocardial hypertrophy of the LV, normalizes the work of the heart, and also the isozyme profile of myosin. Promotes increased regional blood flow in muscles, increases cardiac index and IOC, heart rate does not increase.
Generic Aceon helps to reduce the concentration of uric acid in people with hyperuricemia, increases the concentration of HDL. Increases renal blood flow, the glomerular filtration rate does not change.
In patients with CHF possibly reduce blood pressure, increases tolerance to physical loads, and reduces the severity of clinical signs of heart failure. The maximum hypotensive effect can be observed after 4-6 hours, but it persists throughout the day. After a month of therapy, the hypotensive effect stabilizes. The termination of therapy with the syndrome of "withdrawal" is not accompanied.
It is inherently a prodrug that helps to form in the body an active metabolite of perindoprilat. As a result, this all leads to a decrease in afterload and preload, as well as resistance in the pulmonary vessels, an increase in the minute volume of the heart and increased tolerance to the load. The drug is excreted from the body by the kidneys.
In what kind of disease treatment Aceon is helpful?
Is used for:
•treatment of hypertension;
•prevention of recurrent stroke (in combination with indapamide) in individuals who have suffered a transient impairment of the blood circulation of the brain by an ischemic type or stroke;
•treating of CHF;
•reduction of cardiovascular complications in people with stable ischemic heart disease.
What should I tell my health care provider before I take Generic Aceon?
In some situations, the use of this drug is contraindicated and is not recommended for anything - it can theoretically lead to undesirable negative consequences that is why it is important to read instruction especially if you buy Aceon without prescription. Such situations include:
•hypersensitivity to the key component of the drug, or by-products;
•pregnancy and the period of feeding;
•a general hypersensitivity to ACE inhibitors.
There are situations when, in theory, the use of this drug is permissible, but extremely undesirable. In this case, you need to consult a doctor about how you should proceed in your situation to effectively minimize risks.
How should I take Aceon?
It is taken in the morning, before breakfast, internally.
Dosage information
Initially, this drug is taken at 1-2 mg per reception, once a day. Then it is possible to proceed to maintenance doses, which can be twice bigger as long if the patient exhibits congestive heart failure, or multiplied by 4 in case of hypertension. In any case, it is still necessary to take the drug in one session.
For people older than 70, patients with CHF, against a background of hypertension renovascular and on the background of preliminary treatment with diuretics, the initial dose is 2 mg / day (at a time). If necessary, after one or two weeks, the dose may be increased to 4-8 mg / day.
What may interact with Generic Aceon?
Taking medication helps to increase the severity of the action of sulfonylurea and insulin. Tricyclic antidepressants, baclofen, saluretics, tantipsychotic drugs increase the hypotensive effect, increase the likelihood of orthostatic hypotension. NSAIDs and GCS make the hypotensive effect of Aceon less pronounced (delay electrolytes, water). K + and potassium-sparing diuretics increase the likelihood of hyperkalemia. The parallel use of Aceon and drugs that cause hyperkalemia is not recommended, except in cases of severe hypokalemia.
Myelotoxic drugs increase myelotoxic effect. With the combined use of lithium drugs, it is possible to slow their elimination from the body.
What should I watch for while taking Aceon?
During and before therapy, the concentration of urea, electrolytes and creatinine should be determined.
What side effects may I notice from Generic Aceon?
The drug rarely causes any Aceon side effects, but this does not mean that they are completely eliminated. At the first manifestations of deviations of this kind, it is necessary to react to them promptly and correct the course of treatment, choosing the best solution together with the doctor.
Side effects are grouped according to the system to which they primarily affect:
• Cardiovascular system: there may be a fairly strong drop in blood pressure, as well as the symptoms that are associated with it.
• Urinary system: kidney failure may develop, or become worse already present.
• Digestive system: dry mouth, constipation, diarrhea, nausea, vomiting, pain in the mouth, or change in taste perception may occur.
• Respiratory organs: often difficult to breathe or dry cough, rarely enough bronchospasm.
• Nervous system: increased fatigue, dizziness, headache, deterioration of appetite, vision problems, ringing in the ears, paresthesia, convulsions, in rare cases, there may be a decrease in mood and insomnia, even more rarely confusion may occur.
• Allergic reactions: skin rashes or itching may begin, angioedema may be less likely, including spreading to the digestive tract, as well as urticaria, rarely exudative erythema multiforme occurs.
• Other: proteinuria, hypercreatinemia, hyperkalemia, hyperuricemia, leukopenia, neutropenia, thrombocytopenia, hypogemoglobinemia, hematocrit lowering, agranulocytosis, increased activity in liver transaminases, pancytopenia, hemolytic anemia or hyperbilirubinemia may occur.
Where can I keep Aceon?
Keep the drug in a place that children could not reach. Other conditions for storage of the medicine are not required. It can be used during three years from the manufacture date. Also you can buy Generic Aceon online in different international pharmacies like Australia online pharmacy.
