The drug is an antipsychotic agent that has an atypical effect. At standard dosages, it exhibits antipsychotic activity. The drug shows a high degree of affinity for serotonin 5HT2 receptors in the brain, as well as histamine, a1-adrenoreceptors, has a lower activity to a2-adrenergic receptors. In addition, there are data on the ability of quetiapine to interact with histamine, choline and adrenoreceptors. During the research, antipsohotic activity manifested itself in standard sites. The use of this drug helps to depress the symptoms of schizophrenia, interferes with the development of psychomotor agitation, reduces aggressiveness, and has a positive effect on memory. A large number of good reviews about this drug, indicates its high level of effectiveness of the impact on the disease.
Use of the medication Seroquel helps to suppress the symptoms of schizophrenia, effectively eliminates manic state, prevents the development of psychomotor agitation, reduces aggressiveness, and normalizes the memory and cognitive abilities of a person.
It should be noted that taking the drug does not promote prolactin in the blood plasma, which is very important, as it prevents the development of serious Seroquel side effects. When ingested, the active substance is completely absorbed into the blood. Eating can change the bioavailability index, but to a small extent.
The distribution according to the tissues of the organism is predominantly uniform. The maximum content of quetiapine is noted in the liver and structures of the central nervous system. Metabolization of the drug occurs in the liver cells, with the formation of both inactive and active metabolites. Half-life is about 7 hours. At least 70 percent is excreted by the excretory system.
In what kind of disease treatment Seroquel is helpful?
Seroquel is used in the treatment of acute and chronic psychoses, including schizophrenia; depressive episodes in the middle, high severity, manic episodes in the structure of bipolar disorder. Doctors remind you of the unacceptability of uncontrolled use of any neuroleptic drugs. The choice of a safe dosage should be dealt with only by a psychiatrist who has all the necessary data. If you buy Generic Seroquel online read the instruction carefully.
What should I tell my health care provider before I take Generic Seroquel?
Contraindications include:
application of CYP3A4 inhibitors, erythromycin, azole antifungal drugs together with the drug in one time interval;
sensitivity to the constituents of the drug;
age is less than 18 years.
Relative contraindications: hepatic insufficiency, convulsive attacks, arterial hypotension, cerebral circulatory disorders, elderly age.
How should I take Seroquel?
Reception should be carried out twice a day, with no binding to eating. It is prescribed either once a day before going to bed, or twice a day, regardless of the meal.
Dosage information
In the treatment of chronic psychosis, the Seroquel dosage is applied in the first four days: 50 mg, 100 mg, 200 mg, 300 mg. Based on the indicators, the volume can be in the range of 150-750 mg. In the treating of manic episodes used in the first four days, this dosage: 100 mg, 200 mg, 300 mg, 400 mg. Based on the indicators, the volume can be in the range of 200-800 mg. Doses of the drug may vary by the attending physician, based on the specifics of the course of the disease and the characteristics of the patient. It is recommended to carefully take the drug to people who have an unhealthy cardiovascular system, brain diseases, hypotension, and those patients in whom anamnesis epileptic seizures are detected.
What may interact with Generic Seroquel?
Special care is required in the appointment of drug Seroquel in combination with other drugs acting on the CNS.
What should I watch for while taking Seroquel?
The drug may contribute to the manifestation of orthostatic hypotension at the initial stage of the drug. When revealing the development of malignant form of neuroleptic syndrome, it is necessary to cancel the drug.
Do not apply this medicine to patients who are hypersensitive to the drug or intolerant of any substance that makes up the drug. Also, it is recommended to discuss with the doctor the peculiarities of the interaction of Seroquel medication with other drugs, if simultaneous use is recommended. It is forbidden to take Seroquel during pregnancy and by lactating women.
Carrying out treatment with the drug, you should avoid the use of alcoholic beverages, since it is possible to develop a toxic effect, suppress the respiratory center. Considering the fact that the drug can develop a retardation reaction, you need to restrain from engaging in possible hazardous activities.
What side effects may I notice from Generic Seroquel?
This medication, being a synthetic drug, is capable of causing many side negative symptoms. These will include:
• drowsiness;
• constipation;
• orthostatic hypotension;
• indigestion;
• dizziness;
• lakopenia;
• tachycardia;
• dry mouth;
• dizziness;
• moderate and mild asthenia;
• pharyngitis;
• a subfebrile condition;
• myalgia;
• decreased visual acuity;
• peripheral edema;
• dry skin;
• rhinitis;
• pain in the lumbar region of the back;
• increase in body weight (especially in the first two weeks from the start of therapy);
• pain in the chest area.
Less often, but the possibility of developing such symptoms as:
All these above-described signs manifest themselves quite often, judging by the numerous Seroquel reviews of patients about this drug. In the case of a sharp discontinuation of taking large doses of the drug, it is possible to manifest such reactions: insomnia, vomiting, nausea.
Where can I keep Seroquel?
Keep the tablets under standard conditions: out of the reach of children, high humidity and direct sunlight, at room temperature. The shelf life of this drug is 4 years from the date it was released from production. You can buy Seroquel without prescription in Finland online pharmacy.
