Rythmol (Propafenone)

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What is Generic Rythmol?

Rythmol is an antiarrhythmic drug. Its effect is based on blockade of calcium channels and beta-adrenoreceptors, as well as on the membrane-stabilizing action exerted on myocardiocytes.

Rythmol begins to act about an hour after ingestion; the maximum effect is achieved in a couple of hours and lasts up to about twelve hours, depending on the specific characteristics of the body.

After consumption, more than 95% of the drug is absorbed. It is excreted by the kidneys, and also partially with bile. In liver failure, excretion of the drug worsens. The use of the drug is normalized by a doctor. 

If there are active violations of the liver, the dose of Rythmol is about 20% of the usual, and if the kidney function is impaired, the dose becomes half as large. With changes in the patient's condition, the dose is promptly adjusted by the doctor, or the drug is discontinued for a while.

In what kind of disease treatment Rythmol is helpful?

The drug can be used for a fairly wide range of problems, but it is most effective in these cases:

• The need for prevention, as well as treatment of extrasystoles of the ventricular or supraventricular type.

• Prevention of monomorphic stable ventricular tachycardia.

• Prevention, as well as treatment of rhythm disturbances of paroxysmal type. For example, here can be attributed the syndrome of Wolff-Parkinson-White and a number of other abnormalities.

• Prevention, as well as treatment of atrial-ventricular tachycardia.

What should I tell my health care provider before I take Generic Rythmol?

In some cases, the drug should not be used, because it has a number of specific contraindications. Among other things, they include:

• Most cases of cardiogenic shock.

• Severe bradycardia.

• Severe forms of heart failure of a chronic type, including an uncontrolled form of this deficiency.

• Severe hypotension of the arterial type.

• Blockade of the sinoatrial type, as well as problems with intracirculation.

• Myocardial infarction.

• Blockage of the legs of the so-called bundle of His.

• Intraventricular blockage of bifascicular type.

• Lactation period.

• AV blockade II or III degree.

• Intoxication with digoxin.

• Hypersensitivity to isolated components of this drug.

• Child or adolescent age of the patient.

These are situations where the use of the drug in principle should not be carried out. There are also situations where use theoretically can be permissible, but it must be done with extreme caution and must be supervised by the attending physician:

Myasthenia gravis;

Arterial hypotension;

Electrolyte disturbances;

Renal or hepatic insufficiency;

Presence of a pacemaker or similar device;

Hepatic cholestasis;

COPD;

Heart failure;

Age over 70 years and so on.

In any non-standard situations it is best to consult a doctor once again. Read an instruction in the package if you buy Generic Rythmol online.

How should I take Rythmol?

This pharmacological agent is available in tablets and therefore it needs to be used internally. Take it traditionally after eating, swallow whole and wash it down with water.

Dosage information

First, 150 mg three times a day is prescribed. Then the dose is systematically increased until it reaches the maximum, 900 mg per day for three servings. In severe situations, appoint 900 mg per day.

What may interact with Generic Rythmol?

The drug Rythmol can definitely interact with other drugs, changing its own effect, or changing their effect on the human body. This must necessarily be taken into account, because otherwise you can severely damage your own body. Next, several examples of drug interactions are listed, but the matter may not be limited to them alone. If you are taking any medications, you must always check with your doctor if joint use is acceptable.

• When interacting with lidocaine, the cardio-depressive effect may be markedly increased.

• When used with warfarin, metabolism will be blocked, so the effect of the latter will intensify.

• If you take propranolol, digoxin, metoprolol, as well as anticoagulants of indirect action or cyclosporine simultaneously with the drug, then the concentration of the latter in the blood plasma will increase noticeably.

• When used with tricyclic type antidepressants, as well as with beta-blockers, antiarrhythmic action may increase.

• If local anesthetics are taken at the same time, there is a greater chance that the CNS will be affected.

• Concentration of the drug in plasma when used with quinidine or cimetidine increases by about twenty percent, with similar use with rifampicin, on the contrary, decreases.

• If the drug is taken in conjunction with amiodarone, then one of the characteristic subspecies of tachycardia can develop.

• If medications that inhibit bone marrow hematopoiesis are taken, the risk of myelosuppression may increase.

• When used with drugs that depress the AV node and / or the sinoatrial node, the likelihood of developing a variety of side effects may increase.

What should I watch for while taking Rythmol?

In some situations, the drug may have undesirable effects. Far from the fact that they will be provided, the probability of this is usually one percent or less, but it is still necessary to take into account that this is also possible.

In the case of the first manifestation of such symptoms, it is necessary to consult a doctor promptly so that it corrects the treatment or selects an alternative drug that does not have similar side effects. Also it is possible to buy Rythmol without prescription.

What side effects may I notice from Generic Rythmol?

Rythmol side effects can apply to different systems of the body:

• Heart and blood vessels. There may be worsening of the course of heart failure, ventricular type tachyarrhythmia, AV dissociation, bradycardia, angina pectoris, sinoatrial blockade, AV blockade, problems with intraventricular permeability, and supraventricular tachyarrhythmias. If the drug is taken in especially high doses, hypotension of the orthostatic type is possible.

Nervous system. There may be dizziness and headaches, in slightly more rare cases, convulsions and blurred vision occur.

Digestive system. Bitterness and pronounced dry mouth, nausea, markedly change in taste.

• Hooded. There may be leukopenia and thrombocytopenia, as well as agranulocytosis, antinuclear antibodies may appear, and the average bleeding time may also increase.

• Sexual system. Sometimes a decrease in potency and oligospermia may occur.

• Allergies. Sometimes there are allergic reactions, including a lupus-like syndrome, reddening of the skin, itching, urticaria, exanthema and skin rash.

• Other. Bronchospasm, weakness, rash on the skin of the hemorrhagic type.

Where can I keep Rythmol?

The drug should be stored for no more than 3 years at a temperature under 70 ° F in a damp place where light does not reach and which is not accessible to children. You can also purchase it in international pharmacy like Denmark online pharmacy.

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Active Ingredient:

Propafenone

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Active Ingredient