It is a drug that has a diuretic and hypotensive effect. Its use helps to reduce the reabsorption of chloride and sodium ions in the proximal tubules of the kidneys, and also weakens the excretion of calcium, magnesium and uric acid ions.
Microzide drug enhances the concentration ability of the kidneys and is perfectly absorbed into the gastrointestinal tract. This drug reduces the sensitivity of the vascular wall to the exciting effects of mediators.
The diuretic effect of Microzide occurs half an hour after its administration and reaches a maximum in eight to twelve hours. There are not many reviews of the drug, but you can find the ones where patients write about the side effects. Users write that most often with the correct selection of the dosage of the drug they note a full recovery.
In what kind of disease treatment Microzide is helpful?
A medication can be prescribed in the following cases:
1. Arterial hypertension.
1. Non-diabetes mellitus.
2. Edema syndrome of various nature.
3. Gestosis.
4. Psoriasis.
5. Glaucoma.
6. Nephrite.
7. Nephrosis.
8. Cirrhosis of the liver with portal hypertension and edematous-ascitic syndrome.
9. Heart failure in a stagnant form.
10. To prevent the occurrence of stones in the urinary tract.
What should I tell my health care provider before I take Generic Microzide?
Microzide medication is not allowed to be accepted in the presence of the following circumstances:
1. Excessive sensitivity to this drug.
2. Gout.
3. Complex forms of diabetes mellitus.
4. Hypercalcemia.
5. Hypokalemia.
6. Hyponatremia.
7. The first trimester of pregnancy and the time of breastfeeding.
8. Severe renal insufficiency.
9. Anuria.
10. Addison's disease.
How should I take Microzide?
This medication is taken internally with a glass of water.
Dosage information
To reduce blood pressure, the above-described drug is prescribed in a dosage of 25 to 50 milligrams per day.
Patients with edematous syndrome are recommended to take 25 to 100 milligrams of this medication per day once in the morning or in two divided doses in the morning.
Older people should take 12.5 milligrams one or two times throughout the day, and children between the ages of two months to fourteen years - 1 milligram per kilogram of body weight per day.
The maximum allowed daily dose for children under six months is 3.5 milligrams of medication per kilogram of body weight, for children under two years of age from 12.5 to 37.5 milligrams, and for patients from three to twelve years, 100 milligrams per day, divided into three doses.
After three to five days of treatment, you should take a break for three to five days. For prophylaxis, the drug is used at the indicated dosage twice a week.
With glaucoma, drug Microzide is prescribed at 25 milligrams once in a period of one to six days. The effect of the drug becomes noticeable after one or two days.
Patients with diabetes insipidus should take 25 milligrams of this medication once or twice a day and gradually increase the dose to 100 milligrams in order to achieve a therapeutic effect that is expressed in a decrease in thirst and polyuria. In the future, the dose can be reduced. But remember to read the instruction before the therapy especially if you buy Microzide online.
What may interact with Generic Microzide?
Do not combine it with drugs containing lithium salts, as this will lead to a decrease in the kidney clearance of lithium and increase its toxicity. The combination with drugs designed to reduce pressure, strengthens their effect and requires dose adjustment.
The use of the described preparation together with cardiac glycosides can enhance their toxicity. Microzide enhances the action of peripheral muscle relaxants.
Hypotensive effect is enhanced by barbiturates, beta-adrenoblockers, vasodilators, ethanol, tricyclic antidepressants and phenothiazines.
The drug improves the neurotoxicity of salicylates and the weakening of the effect of oral hypoglycemic drugs, epinephrine and norepinephrine, agents for the treatment of gout, and also reduces the effectiveness of oral contraceptives.
Cholestyramine lowers the absorption of Microzide. Do not combine with methyldopa, as this can provoke the development of hemolysis.
The described drug reduces the excretion of quinidine. It is also able to reduce the amount of iodine that binds to serum proteins, but it does not show any symptoms of disruption of the thyroid gland.
What should I watch for while taking Microzide?
With prolonged use, it is necessary to monitor the concentration of electrolytes in the blood plasma, as well as adhere to a diet that includes foods high in potassium.
During the period of use of Microzide, care must be taken when driving vehicles and engaging in potentially hazardous activities that require intense attention and speed of psychomotor reactions.
During the first three months of the expecting period for the child, the drug cannot be taken, but in the following months, this drug can be prescribed to a woman by her doctor in order to get rid of late toxicosis.
What side effects may I notice from Microzide?
To Microzide side effects, the appearance of which can trigger the use of drug, it is possible to attribute the following:
Keep the above described preparation in a dry and dark place, not accessible to children, at temperatures up to 25 degrees Celsius. You can even buy Microzide without prescription if you don’t have opportunity to do it in regular pharmacy and the most convenient way to do is to choose Canada online pharmacy.
