Femara (Letrozole)

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What is Generic Femara?

The drug has the same international name and refers to antitumor agents. The drug is available in the form of pills. Its action is based on the properties of aromatase inhibitor - which is an inhibitor of the synthesis of estrogens. In the process of use, there is an anti-estrogenic effect. The processes of reducing aromatase activity are due to competitive binding to the prosthetic part of the cytochrome P450. In the postmenopausal period, estrogens are formed with the participation of the aromatase enzyme, which turns androgens, which are synthesized in the adrenal glands, passing into estradiol and estrone. Daily use of this drug leads to a marked decrease in the concentration of estrone, estradiol and estrone sulfate. The percentage reduction in concentration can reach 95% of the initial value. In the process of Letrozole exposure in patients, a decrease in the concentration of circulating estrogens and inhibition of synthesis in the tissues of breast tumors is observed. The result of the action is a regression of tumors and a reduction in relapse, as well as mortality.

Absorption occurs quickly and completely in the GI tract. When used, a violation of the synthesis of steroid hormones in the adrenal glands is not observed at all. The process of treatment with medication Femara practically does not increase the frequency of osteoporosis. The frequency of bone fractures in patients taking the drug is practically the same as in healthy people.

It is often used for:

• prevention and treatment of gynecomastia;

• decrease in the concentration of estrogen in the blood;

• increase the concentration of anabolic hormones in the blood;

• improving the quality of the musculature athlete (the desired result is achieved by suppressing the effect of estrogens);

• prevention of hypertension.

In what kind of disease treatment Femara is helpful?

The instruction describes the main indications and contraindications in which the drug is prescribed for use, however, only the treating specialist should select the dosage and determine the course of treatment. The best reviews Femara received when it is used in the treatment of common hormone-dependent breast cancer in the postmenopausal period. Also it is recommended for use in the early stages of disease in postmenopausal women.

What should I tell my health care provider before I take Generic Femara?

If the following contraindications are found, there may be bad consequences:

• pregnancy;

• childhood;

• lactation and hypersensitivity.

How should I take Femara?

Femara pills are taken orally. The medication can be taken regardless of the meal schedule.

Dosage information

This drug is prescribed only by a doctor with sufficient experience of cancer treatment of breast cancer. At the same time, adjuvant therapy is effective (auxiliary additional surgical and radiotherapy).

For adults is suitable daily use of the preparation in a dosage of 2.5 mg. In conjunction with adjuvant therapy, treatment should last no longer than 5 years. If patients have noticed any signs of the development of the disease, using of drug should be stopped immediately. In patients with impaired functioning of the liver and kidneys, a change in the dose of the drug is not necessary.

What may interact with Generic Femara?

In clinical trials interactions of Femara drug with other pharmacological agents were conducted. Clinically significant results were not obtained during these studies. The appointment of this medication cannot be combined with taking any medications that have an estrogen in their composition. In this case, the effect of Letrozole anti-hormonal action will be decreased.

What should I watch for while taking Femara?

Before the appointment of Femara, it is necessary to conduct a test for the sensitivity of tumor cells to estrogen. In the absence of such sensitivity, this drug is not used. The expediency of prescribing to patients without lymph node involvement is determined individually: the degree of malignancy, tumor size, the presence of estrogen receptors, and age are taken into account.

Before you buy Generic Femara you should be familiar with the contraindications to taking the drug. So, if you have any problems with the cardiovascular system, you cannot use medicament. The thing is that, counteracting the side effect of estrogen, the drug blocks its useful properties. As a result, are possible problems with blood vessels and heart.

During the period of treatment, it is not recommended to drive a car and other activities that require increased attention and speed reaction.

What side effects may I notice from Generic Femara?

Most often, undesirable phenomena from taking this medication are not critical. Adverse reactions that require withdrawal of the drug are rare. Undesirable reactions include general weakness, periodic headaches, thinning of the nails, decreased quality of hair, bleeding, weight gain, increased sweating.

It also can be:

• dizziness;

• nausea;

• constipation;

• indigestion;

• vomiting;

• bulimia;

• leukorrhea;

• anasarca;

• peripheral edema.

Fortunately, there have been no cases of overdose with Femara remedy until today. Therefore, the actions in cases of overdose are not known. If you have any questions, it is best to contact your doctor.

Where can I keep Femara?

Keep the drug in a dry place, at a temperature of no higher than 25 ° C. Do not let kids or animals play with this medication. To save your money you can buy Femara without prescription in Portugal online pharmacy.

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Active Ingredient:

Letrozole

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Active Ingredient