Zyvox (Linezolid)

What is Zyvox?

Zyvox is an antibiotic of the new generation containing linezolid — a synthetic substance of oxazolidinone group.

In what kind of disease treatment, Zyvox is helpful?

Infections caused by susceptible anaerobic and aerobic gram- positive micro-organisms, including infections accompanied by bacteremia, such as:

• Nosocomial pneumonia

• Community acquired pneumonia

• Infections of the skin and soft tissues

• Infections caused by Enterococcus, including vancomycin-resistant strains

Linezolid is active only in relation to gram positive bacteria.

What should I tell my health care provider before I take Zyvox?

Taking antibiotics is now a fairly widespread method of healing. Nevertheless, the level of awareness about these medications is extremely low. The healing with antibiotics should be approached with a certain degree of responsibility. Prior to begin receiving the tablets read these contraindications and tell the physician if you have:

• Noted susceptibility to linezolid or any other element of the Zyvox

• Take any medicines that suppress monoamine oxidase A and B, or within fortnight after receiving such drugs

• Unchecked arterial hypertension, pheochromocytoma, carcinoid, thyrotoxicosis, bipolar depression, schizoaffective violation, severe episodes of vertigo

• You’re using serotonin reuptake inhibitors, tricyclic antidepressants, 5-NT1 agonists of serotonin receptors (triptans), direct and indirect sympathomimetic, vasopressors, dopaminergic compounds, buspirone or Petydyne

How should I take Zyvox?

Drink the tablet with a full cup of pure, non- aerated, not cold water. The antibiotic advised to take at the same time with proportionate intervals to maintain a constant concentration of active ingredient in the blood. Ask the physician about the correct intake of these tablets, such as whether you can use it mixed with meals, or regardless of the diet, this factor can influence the success of healing. Very important: if you have started a course of Zyvox, and everything went well, and now all the symptoms has disappeared, continue to take the assigned antibiotic. It is indispensable to complete a full course of Zyvox, it usually ranges from 5 to 10 days — the duration must be determined by the attending physician. The fact that illness symptoms weakened, means, above all, that weakened microorganisms causing them. But weakened - does not mean completely killed. Always remain a certain amount of particularly resistant bacteria that can multiply again if you stop taking antibiotics ahead of schedule. Ask your physician if there are questions on taking the medicine. As well, for an additional data you can look for reviews while you buy Zyvox online.

Zyvox dosage information

For individuals older than 12 years with nosocomial and community-acquired pneumonia and problematic infections of the skin and appendages typically suggest 600 mg of linezolid twice a day. The course duration makes 10-14 days.

For sick over 12 years in ailments correlated with Enterococcus faecium, typically suggest 600 mg of linezolid twice a day for 14-28 days.

For diseased more than 12 years old with uncomplicated infections of the skin and appendages generally advised 400-600 mg of linezolid 2 times/day for10-14 days.

When healing with Zyvox is pertinent to maintain the exact 12-hour intervals between receptions.

The largest allowed amount of Zyvox makes 600 mg every 12 hours.

Do not take these tablets longer than 28days, since the safety of the course has not been clinically validated.

For patients going through dialysis, linezolid must be taken after the dialysis session (nearly 30% of the dose of Zyvox is output in a 3-hour long hemodialysis session).

What may interact with?

Probable an increase in arterial pressure when Zyvox is combined with sympathomimetics (direct and indirect action), dopaminergic agents and vasopressors.

Zyvox can lead to serotonin syndrome when taken with serotonergic drugs.

Against the background of therapy with Zyvox should not be eaten large amounts of foods rich in tyramine (overripe fruit and chocolate, wine and beer, yogurt, nuts, beans, smoked and canned meat); not advisable to use more than 100 mg of tyramine while taking linezolid. Large doses of tyramine can lead to the development of the vasopressor effect.

Linezolid invertible aselectively inhibits MAO, the doses used for the antibiotic therapy do not exert marked clinical impact on MAO, and however the joint use with MAO inhibitors is undesirable.

The pharmacokinetics of linezolid or Aztreonam does not change at concurrent usage of these medicines.

The pharmacokinetics of linezolid or Gentamicin does not change at concurrent usage of these medicines.

What should I watch for while taking Zyvox?

If one day you physician has prescribed Zyvox, it does not mean that you can take it with similar symptoms or advise it to someone else.

There is no decent info on use of Zyvox by pregnant women. Results of animal researches have demonstrated the presence of reproductive toxicity. There is a peril to the developing infant. Zyvox has not to be prescribed during pregnancy unless the expected superiority surpasses the projected hazards.

Outcomes of animal researches have proved that linezolid and its metabolites may penetrate into the breast milk. Therefore, discontinue lactation along the healing with Zyvox.

Sick should be notified about the possibility of vertigo or phenomenon of visual disturbances while receiving linezolid; it is suggested not to manage motor vehicles and do not work with other complex mechanisms in the event of mentioned events.

Greasy, fried, smoked, canned foods, alcoholic drinks and sour fruits are a load to the liver and digestive system even for a fully healthy person, during the antibiotics therapy they are recommended to be excluded from the diet.

Keep a record of antibiotics that you have used for the last few years, this information will help your health care provider to assign the proper medication.

Zyvox side effects

Collateral actions are provided for guidance to people taking the drug, so they could better orientate in their state of health. One should not think that will manifest all the disorders that are enumerated in this list below. When a preparation is undergoing clinical trials, experts are required to fix every negative consequence, even if it was manifested a single person out of a hundred thousand. Other words, the probability of certain stated conditions is very low. Either way, all the violations that you are experiencing should be examined by a physician.

• Candidiasis or fungal infections

• Headache, taste abnormality

• Blurred vision

• Diarrhea, queasiness, vomiting

• Atypical hepatic activity tests

• Anaphylaxis

• Peripheral neuropathy, convulsions, serotonin syndrome

• Optical neuropathy, occasionally proceeded to deprivation of sight (mainly observed among sick who received Zyvox longer than the superlative approved continuation which makes 28 days)

• Steven – Johnson syndrome

Where can I keep Zyvox?

Keep in the authentic packaging at a temperature below 25 ° C, out of reach of kids. The tablet must be consumes right away after it was removed from the package. Specify with your health care provider where you can get the medication or buy Zyvox online.