It is an active drug, with a semisynthetic lipophilic derivative podophylotoxin. It is produced in the form of capsules. The medication affects tumors, and also triggers the necrosis process inside the malicious cell. Attention! At high concentrations of Etoposide, necrosis of normal, healthy cells is possible.
It is prescribed for the treatment of cancer of lymph nodes, lung or stomach. It can be used as an independent medicine, or in combination with other drugs. Due to its effectiveness Vepesid in general received favorable reviews.
In what kind of disease treatment Vepesid is helpful?
During the course of the next series of diseases and disorders, Vepesid medication received the most positive feedback. The positive effect of the drug was noticeable in the treatment of very rare germinogenic tumors (a group of formations caused by the germ cells of the gonads). Also, the medicine actively fights against small-cell and non-small-cell lung cancer, stomach cancer. In addition to all of the above Kaposi's sarcoma, on the walls of the blood vessels, which is visible on the mucous membranes and skin, is also included in the therapeutic field of medication.
What should I tell my health care provider before I take Generic Vepesid?
It will not be helpful for patients who suffer from:
• arrhythmia;
• chicken pox;
• renal and hepatic insufficiency, with an affected mucous system;
• also to pregnant women and newly-born patients during breastfeeding.
It is forbidden to take Vepesid for people who are hypersensitive to the components of the medicine, or patients with myelosuppression (reduced number of blood cells that form in the bone marrow).
It is strictly forbidden to take it for pregnant women! Tests of this drug were not performed on pregnant women. But when studying the reaction of the body of pregnant rats and rabbits, scientists received information about embryo development disorders and the toxicity of the given drug to the fetus. It is also worth noting the ban on the use of this medicine for children under 2 years old.
How should I take Vepesid?
It is taken internally and regularly, washing down with tap water.
Dosage information
On average, the suitable dose of the drug is 50 mg per day. The duration of the course is 5 days, after which it is necessary to take a break in several weeks. The repeated course is appointed only after the picture of periphyric blood normalizes.
This drug is prescribed for daily intake within 21 days at a dosage of 50 mg / μV on the surface of the body. To prepare the solution, use only water. The route of administration and the intervals in therapy should be determined individually by your health care provider. Also, the amount of the drug may vary depending on the effectiveness of the effect, or on the tolerability of the drug.
Attention! The solution must be prepared immediately before the procedure itself. Do not store the composition for more than 48 hours. Remember to mix the drug with other medications strictly forbidden!
Also, it is worth giving preference to specialized inpatient treatment, under the supervision of an experienced physician. Do not forget to take care of effective contraceptives, since taking this medication is not compatible with pregnancy.
What may interact with Generic Vepesid?
Drug Vepesid exerts a more pronounced antitumor effect when it is used together with cisplatin. However, in many patients who received such complex therapy, there was a violation of excretion of Etoposide. It also has an immunosuppressive effect. Therefore, its use is not recommended simultaneously with live vaccines - this can lead to the emergence of infectious pathologies. Vaccination is possible at least 3 months after the end of treatment with Vepesid. In addition, this drug should not be mixed with any other substances and used in conjunction with alkaline solutions.
What should I watch for while taking Vepesid?
Ethanol, which is part of the drug, can harm patients who suffer from liver disease, alcoholism, epilepsy. The risk zone also includes children. The duration of the course of treating along with the dosage should be determined by a doctor with experience in the therapy. You can work with the medicine only in gloves. In case of contact with skin, wash immediately with soap and water.
Care should be taken when managing complex machinery and vehicles, since the incompatibility of the drug with these activities is noted. Vepesid is characterized by a mutagenic effect.
What side effects may I notice from Generic Vepesid?
The strength and frequency of Vepesid side effects in patients directly depends on the intervals between injections and dosages. As a rule, in the case of combined chemotherapy, the frequency, as well as the severity of these effects, may increase. Most often, patients suffer from:
nausea and vomiting;
pain in the stomach;
puffiness of the face;
cough;
fever and weight loss;
baldness;
itching and scabies;
pain in the back;
phlebitis;
possibly locally irritating effect, up to the fixation of necrosis in case of getting the drug directly under the covers of the skin;
manifestations of a toxic nature, in the form of a decrease in the number of leukocytes and granulocytes, with the lowest content of granulocytes being fixed on the 7-14th day of course, with respect to platelets, the minimum amount is fixed 9-16 days after the use of medication;
Blood indicators are restored, most often, 20 days after the application of the drug.
Less common may be pigmentation, fever, unpleasant taste in the mouth, fatigue, muscle cramps, loss of consciousness.
Where can I keep Vepesid?
Patients should store drug at a temperature of 15-25 ° C, in a dark and dry (low-humidity) place, for children inaccessible. The shelf life is three years. You can also buy Vepesid without prescription in France online pharmacy.
