Detrol La is effective for relieving bladder hyperactivity symptoms, unless the disease develops because of organic reasons. Before treatment, you should be examined to determine the cause of the disease.
Tolterodine is a substance that is a competitive blocker of m-cholinergic receptors. This substance is part of the medicines that are used to treat urological diseases.
In what kind of disease treatment Detrol La is helpful?
Detrol La is used in frequent urge to urinate, which leads to urinary incontinence.
What should I tell my health care provider before I take Generic Detrol La?
The drug cannot be used:
• if the tone of the bladder is increased for organic reasons (due to the aging, damage to the spinal cord, in women - during pregnancy);
• in hereditary violation of carbohydrate metabolism in the body;
• in difficulty urinating;
• severe grade ulcerative colitis;
• megacolon;
• an angle-closure glaucoma that is completely unreachable;
• lack of sucrose-isomaltase;
• intolerance to hereditary fructose;
• glucose-galactose malabsorption;
• mandatory and frequent urge to urinate, which causes are organic;
• up to 18 years.
• pregnant and lactating;
• in some diseases of the digestive system (ulcerative colitis, disruption of the intestine, slow digestion);
• if the patient is diagnosed with myasthenia gravis, an autoimmune disease in which there is an increased fatigue of the muscles.
Very carefully is prescribed Detrol La medication in the following conditions and diseases:
• neuropathy;
• a bradycardia;
• hiatus hernia;
• risk of slowing down the process of emptying the stomach;
• obstructive diseases of the digestive tract (stenosis of the pylorus, for example);
• obstruction of the lower parts with respect to the urinary tract of a pronounced degree;
• hepatic and renal insufficiency (no more than 2 mg of the drug per day);
• simultaneous administration of antiarrhythmic drugs of class IA and class III;
• pregnancy (only for vital necessity);
• lactation period.
Also, it is not possible to apply the drug in case of individual intolerance to its components. Before taking Detrol La, you should always consult with your doctor, as the above is an incomplete list of contraindications for use.
How should I take Detrol La?
The reception of the pill does not depend on the meal. You cannot divide and grind the tablet.
Dosage information
The daily dose, in most cases, is 4 mg. Capsules can be taken once a day, tablets - twice a day (2 times 2 mg). With pronounced side effects or with kidney or liver disease, the daily dose is reduced to 2 mg. The duration of the course is selected by the attending physician. The average is from 1 to 6 months.
With functional disorders of the kidneys and / or liver, receiving Ketoconazole and other strong inhibitors of CYP3A4, patients are given a dose of 2 mg: capsules once a day for 2 mg, tablets twice a day for 1 mg.
What may interact with Generic Detrol La?
When taking medication with other anticholinergic drugs, therapeutic and side effects are mutually reinforced.
Fluoxetine causes a moderate increase in the concentration of Tolterodine in the body. Preparations of M-cholinomimetics weaken the therapeutic effect of main substance. In turn, drug Detrol La weakens the effect of Metoclopramide, Cisapride.
In patients with isoenzyme deficiency of cytochrome P450, the use of Detrol La together with macrolide antibiotics or antifungal agents leads to a significant increase in the concentration of Tolterodine in the blood, which can trigger an overdose.
What should I watch for while taking Detrol La?
Women should take into account that the reception of the drug should be accompanied by reliable contraception. You cannot have a pregnancy in the period of treatment.
It is not prescribed for pregnant and lactating women, because they have increased bladder tone for organic reasons and do not require treatment.
What side effects may I notice from Generic Detrol La?
In general, this medication is tolerated better than preparations of similar actions. When you take the remedy in most cases, there is dryness of the oral mucosa, eyes, nose.
In more than 10% of cases:
Disorders of the digestive function (stool, bloating, vomiting, abdominal pain), impaired tearing.
In 1% of cases:
Headache; dizziness (vertigo); drowsiness; increased fatigue; nervousness; temporary impairment of visual function; weakness; difficulty urinating (dysuria); violation of the eye muscle; weight gain; bronchitis; increased dryness of the skin; sinusitis - inflammation of the mucous membranes of nasal sinuses (a side effect was observed when taking the drug in the form of capsules).
Less than 1% of cases:
Gastroesophageal reflux (throwing the contents of the stomach into the esophagus); confusion of consciousness; hallucinations; heart rhythm disturbances; swelling; flushes of blood to the face; anaphylactic reactions; retention of urine.
Overdosing occurs when taking from 12 mg Detrol La at one time.
Symptoms:
• violation of accommodation;
• frequent painful urge to urinate;
• overexcitement of the nervous system, which is manifested by hallucinations, convulsions;
• increased heart rate;
• impaired respiratory function.
In this case should be performed symptomatic treatment under medical supervision.
Where can I keep Detrol La?
Shelf life is not more than 3 years from the date of production. Store it at room temperature, far away from children. Also it is important to keep it at a room with low humidity because package can be damaged by water. There is a way to buy Detrol La without prescription in international pharmacy like Netherlands online pharmacy.
