Heart diseases are considered today as one of the most common problems, to reduce the risk of developing such diseases will help special medicines, one of the most effective of which is considered Calan. As a result of a decrease in the content of this element, the vessels begin to expand, and the contractility of the myocardium decreases.
The drug has antianginal, anti-arrhythmic and antihypertensive effect, antianginal properties are achieved due to direct effects on the myocardium, as well as due to the effect on peripheral geodynamics. As a result of taking the medication, the transformation of the ATP energy contained in the macroergic bonds into a mechanical action decreases, as a result, the contractility of the myocardium decreases.
Therapy also contributes to a reduction in the need for the myocardium; the drug has a vasodilating and inotropic effect. Its reception provides suppression of the automatism of the sinus node, which leads to an increase in the refractivity period, and as a result, AV conduction decreases.
In the Calan reviews, experts emphasize the effectiveness and affordability of tablets and solutions; it can quickly restore blood pressure and improve your health in other cardiovascular diseases. Most of the patients' reviews are also positive, most often they are satisfied with the effectiveness of treatment. Taking tablets or injecting a solution helps to quickly eliminate the symptoms of hypertension and other signs of heart and vascular disease.
In what kind of disease treatment Calan is helpful?
Calan medication is recommended for use in the following situations:
Hypertensive crisis;
Vasospastic angina pectoris;
Arterial hypertension;
Supraventricular / sinus tachycardia.
Atrial extrasystole;
Atrial tachyarthry.
What should I tell my health care provider before I take Generic Calan?
The Calan instruction indicates the following contraindications:
Severe form of arterial hypotension;
Increased sensitivity to individual components;
Sinoatrial, as well as atrioventricular blockade of the second and third degree.
The state of cardiogenic shock, provided that it did not develop due to arrhythmia;
Heart failure in acute and chronic form (grade IIB-III);
Low blood pressure;
Ventricular tachycardia;
Some syndromes: weakness of the sinus node, Morgagni-Adams-Stokes, Wolff-Parkinson-White;
AV-blockade of 2 and 3 degrees (exceptions concern patients who have an artificial pacemaker installed).
Be sure to read the instruction before taking pills especially if you buy Generic Calan online.
How should I take Calan?
If the doctor has prescribed this drug for treatment, then he must tell you that the tablets are taken during or immediately after a meal. Wash down them with a small amount of liquid.
Dosage information
The drug can be taken only as prescribed by the doctor, self-medication is prohibited. Dosage is calculated on an individual basis:
Age Dosage Multiplicity:
Age
Dosage
Frequency
Adult patients
40-80 mg
three times a day
children from six to 14 years
60 mg
four times a day
children up to six
40-60 mg
four times a day
The drug is also administered intravenously; the procedure involves mandatory ECG monitoring, heart rate and blood pressure. A single adult dose is 5-10 mg, in the absence of the effect, repeated administration of the drug in the same dose is envisaged.
The maximum daily dose is 480 mg, for patients with a dysfunction of the liver, the dose is 120 mg. For the form of the drug with prolonged action, there is an increase in dosage with a simultaneous decrease in the frequency of administration. Before starting treatment, a doctor should be warned about all diseases and medication treatment.
What may interact with Generic Calan?
When prescribing the drug, the doctor should find out what other medicines the patient drinks. Please note the following:
• When combined with inhalation anesthetics, antiarrhythmic drugs or beta-blockers, cardiotoxic effect is increased (pressure decreases, myocardial contraction frequency decreases and heart failure develops).
• Combination with diuretics and antihypertensive medications enhances the hypotensive effect.
• With concomitant administration of this medication and Digoxin, the concentration of the last may increase due to the fact that the kidneys begin to show worse.
• The effect of the drug is weakened when combined with Phenobarbital and Rifampicin.
• With acetylsalicylic acid, the risk of bleeding increases.
• Combination with muscle relaxants increases the effect of the latter.
• The level of main substance in the blood increases with the use of Ranitidine and Cimetidine.
• The likelihood of developing a neurotoxic effect is enhanced by the simultaneous administration of carbamazepine and lithium.
• The risk of reducing blood pressure, the appearance of arterial hypotension in hypertrophic cardiomyopathy occurs when combined with Quinidine.
What should I watch for while taking Calan?
The patient must monitor his condition when taking the remedy. Even about minor deviations you should report to the doctor.
Drug Calan is contraindicated for use in the first trimester of pregnancy, in the second and third trimester, therapy is allowed only if the benefits of treatment exceed possible harm. During the period of breastfeeding, it is recommended that the medication is discarded, since its components penetrate into the milk.
What side effects may I notice from Generic Calan?
Among the possible Calan side effects are called:
• Arterial hypotension;
• Pronounced bradycardia;
• Appearance of signs of heart failure (occurs when using the drug in large doses);
• Redness of the face;
• AV blockade.
The digestive system can also negatively react to taking the medication. Some patients complain of nausea, vomiting, and the appearance of constipation. Sometimes there is a transient increase in activity of hepatic enzymes. From the central nervous system may appear such complications: dizziness and headache. In rare cases, there is increased excitability or retardation, fatigue. Allergy sufferers may notice the appearance of an itch or rash when taking the drug. Among other adverse reactions, the appearance of peripheral edema is called.
Where can I keep Calan?
This drug is recommended to be stored in a dark place protected from children. Its properties persist for five years. You can also buy Calan without prescription in Greece online pharmacy.
