Zyprexa (Olanzapine)

The international name of this drug is olanzapine. It belongs to the group of neuroleptics and is an antipsychotic. The drug is available in the form of dispersible tablets, lyophilizate for the preparation of solutions intended for intramuscular injection, coated tablets, as well as in tablets coated with membranes. 

The pharmacological action of this drug appears in the antipsychotic effect. The active substance differs in its related qualities and indices with dopamine, histamine, muscarinic and serotonin receptors. The use of the drug makes it possible to selectively reduce the excitability of mesolimbic neurons of dopaminergic neurons. The drug can have a minor effect on the nerve washing paths that participate in the regulation of motor functions of the body. The use of the drug significantly reduces the conditioned protective reflexes, as well as negative productive symptoms.

Since the drug is intended to affect the nerve nodes of the body and parts of the brain, there is use must be strictly controlled only by the appropriate specialist. The instruction contains a detailed description of contraindications and indications, which should be taken into account when prescribing the drug, but nevertheless, it is not enough for setting the doses and the course of treatment. Also if you already consulted with doctor you can buy Generic Zyprexa online.

Based on Zyprexa reviews, as well as laboratory studies, this medication proved to be the best way to treat:

• Schizophrenic psychosis (acute, preventive and prolonged anti-relapse treatment), psychotic disorders with productive (including delusional, hallucinogenic), or negative (emotional flatness, decreased social activity, poor speech) symptoms and accompanying affective disorders;

• Bipolar disorder (mono- or combined treatment (with lithium or valproic acid)): acute manic or mixed episodes with or without psychotic manifestations and with / without rapid phase changes;

• Repeated bipolar disorder (with efficacy of the drug in the treatment of the manic phase);

• Depressive conditions due to bipolar disorder (with fluoxetine).

In addition, the use of Zyprexa is recommended for the manifestation of acute manic or mixed episodes that occur with or without acute phase changes.

Don’t use this medication in the presence of the following contraindications:

• Angle closure glaucoma;

• Hypersensitivity to the active substance;

• Coma;

• Youth and children's age;

• Severe CNS depression;

• Kidney failure;

• Liver failure;

• Hyperplasia of the prostate;

• Myeloproliferative diseases;

• Hypereosinophilic syndrome;

• Epilepsy;

• Pregnancy;

• Lactation period;

• Paralytic intestinal obstruction.

Age restriction is valid for patients under 18 years of age.

The drug should be taken once a day internally. Considering the fact of the lack of influence of food on the assimilation of the drug, it can be taken regardless of food. If there is abolition in its admission, it is desirable to gradually lower the Zyprexa dose.

In the case of schizophrenia, the initial dose is recommended in the amount of 10 mg per day. In case of episodes of mania, 15 mg if it is monotherapy and 10 if combined.

The intake of ethanol can enhance pharmacological effects of Zyprexa medication, for example, sedation. You may feel drowsy if you take it in combination with antidepressants or medications to treat anxiety or drowsiness (tranquilizers).

Tell your doctor if you currently take or have recently taken any other medicines. In particular, tell your doctor if you take medications that:

• cure for Parkinson's disease;

• carbamazepine (antiepileptic and stabilizing drug), fluvoxamine (antidepressant) or ciprofloxacin (antibiotic), as this may require dose changes.

In patients with psychosis, which is induced by the agonist, during the course of Parkinson's disease, there is often a significant increase in Parkinsonism and hallucinations. Although the drug Zyprexa instruction describes indications and contraindications for the use of this medication, only the treating specialist can prescribe the course of treatment and dosages.

If there is a change in lipid levels, you need to adjust the therapy.

You should be careful when using the drug in the presence of paralytic intestinal obstruction, hyperplasia of the prostate gland organ.

To avoid Zyprexa side effects and achieve maximum effectiveness in the treatment of the drug, it is necessary to strictly adhere to the dosage and course of treatment prescribed by the treating specialist.

If the rules for taking this medication are violated, the following consequences may occur:

• drowsiness;

• weight gain;

• asthenia;

• increased appetite;

• akathisia;

• vomiting;

• peripheral edema;

• arterial hypotension;

• dizziness;

• bradycardia;

• dry mouth;

• constipation;

• bulimia;

• orthostatic hypotension;

• gynecomastia;

• galactorrhea;

• hepatitis;

• increased CK;

• pancreatitis;

• exacerbation of diabetes mellitus;

• nausea.

This medicinal product should be stored in a dark place protected from direct sunlight at a room temperature.

It is a well-known and popular product on the pharmacological market and you can buy Zyprexa without prescription in different international pharmacies like Spain online pharmacy.