Procoralan (Ivabradine)

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What is Generic Procoralan?

Procoralan is a modern antianginal and antiarrhythmic drug. It works by inhibiting the functioning of channels of the sinus node. These channels regulate the heart rate and diastolic depolarization in this node.

Reviews about this medicine people leave, as a rule only positive, because the drug normalizes the work of the heart when the cause of the condition is unknown to the doctor. Many of the patients call the drug "miracle agent", because it helps in cases where beta-blockers have not had the desired effect.

Among the negative side of the medication, Procoralan side effects are noted, which are usually expressed in visual impairment. In addition, many patients complain about the high cost of the drug. Doctors, as a rule, leave only positive responses, because this drug remains the only medicine that helps in different situations. Side effects professionals recommend to block medication, without interrupting treatment. This step is explained by the fact that after the withdrawal of Procoralan, the symptoms of heart disease return.

In what kind of disease treatment Procoralan is helpful?

The drug is widely used in the therapy of stable angina pectoris. The medicinal preparation is prescribed under such conditions as:

1. In combination with beta-blockers with improper control of stable angina.

2. If there are contraindications to taking beta-blockers.

3. To reduce the incidence of progression of heart complications.

4. Ischemic heart disease (in combination with other drugs).

5. Symptomatic treatment of angina pectoris.

What should I tell my health care provider before I take Generic Procoralan?

It has an impressive list of contraindications. Before using it, be sure to consult a doctor for their availability and to read an instruction if you buy Generic Procoralan online. The prohibition on taking the drug is in the following cases:

• Intolerance to ivabradine or any of the constituents of the Procoralan drug;

• Bradycardia (heart rate less than sixty beats per minute);

• Extreme degree of left ventricular failure;

• Myocardial infarction;

• Decrease in blood pressure by 20% or more;

• Liver failure;

• Lack of lactase, its complete intolerance;

• Cardiac blockade (AVB) of the third degree;

• The period of CHD, threatening the development of myocardial infarction;

• Artificial pacemaker in stimulation mode;

• Acute heart failure;

• Violation of the sinus pulse through the sinoatrial connection;

• Weakness of the sinus node.

Do not give this drug to children and adolescents who have not reached adulthood. No testing for the safety of the drug for this age group was carried out. Also, it is contraindicated for women in the period of gestation and during breastfeeding.

How should I take Procoralan?

The tablet form of the drug should be taken orally, washed down with plenty of water.

Dosage information

In case of stable angina, the drug is prescribed in the initial dosage of 10 mg (reception should be divided by 2 times). Based on the clinical picture of the disease, the daily dosage can be increased. If symptoms of bradycardia appear, the dosage is reduced to 5 mg. If there is no improvement in the patient's condition, this medication should be discarded.

In the future, the patient must undergo an additional examination in order to choose the right medicine. When HF is recommended to begin taking 10 mg. If after 2 weeks the pulse at rest shows more than 60 beats per minute, then the dosage can be increased to 15 mg.

Correction of Procoralan dosage depends on the frequency of heartbeats:

1. Up to 50 beats per minute - the dosage may not exceed 5 mg.

2. 50-60 beats / min - the dosage should be 10 mg.

3. Above 60 beats / min - the dosage may be 15 mg.

In patients older than 75 years, the daily dosage should not exceed 5 mg. In the future, it can be increased.

Patients who were diagnosed with impaired renal function, the initial dosage should be no more than 10 mg / day. If the patient becomes better, then a further increase in the dose can occur only after 3 weeks.

What may interact with Generic Procoralan?

Do not use it simultaneously with Ziprasidone, Halofantrine and other drugs that extend QT. Under the supervision of a doctor, take the drug along with the following medicines:

• phenytoin, barbiturates;

• rifampicin;

• medicines with St. John's Wort extract;

• non-potassium-sparing diuretics.

What should I watch for while taking Procoralan?

There are rules which you should know if you buy Procoralan without prescription.

1. Patients who have been diagnosed with mild hepatic insufficiency, dosage adjustment, as a rule, is not required.

2. If there are serious abnormalities in the functioning of the kidney or liver, Procoralan drug is administered cautiously. In this case, the doctor must constantly monitor the patient's condition.

3. Doctors do not advise patients during Procoralan treatment to use antiarrhythmic drugs that can prolong the duration of the ventricular complex. If such a need exists, it will require constant monitoring of such a patient and regular transmission of electrocardiography.

4. From the diet, you need to exclude grapefruit juice, since the concentration of the active substance grows one and a half to two times.

5. Doctors do not recommend taking medication during pregnancy and breastfeeding. Data on the safety of such treatment is not available. There is no laboratory research on the safety of this application.

What side effects may I notice from Procoralan?

To study the side effects in detail, extensive trials were conducted involving 15,000 volunteers. The most common were identified:

• loss of vision and distorted perception of light;

• loss of control over blood pressure;

• pain in the head, dizziness;

• seldom there are shortness of breath, digestive problems, muscle cramps.

Photopsy and bradycardia were noted especially often in the first months of therapy. Some of these symptoms gradually disappeared.

Symptoms of a Procoralan overdose are quite severe. The patient develops a long bradycardia and greatly worsens well-being. In this case, it is urgently delivered to a specialized department of the hospital.

Where can I keep Procoralan?

Store the packaging in a safe place that children cannot reach. It must be ensured that direct sunlight does not penetrate there. The air temperature should not be above 25 degrees. Be sure to keep the instructions and the original box. The shelf life of the drug after release is no more than 36 months. It is available in Greece online pharmacy.

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Active Ingredient:

Ivabradine

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Active Ingredient