In general, Nolvadex medication is a non-steroid agent; therefore it has analgesic, antipyretic and anti-inflammatory effect. If we consider the mechanics of the action of the drug in more detail, its main function is to slow down the process of cell division in the body tissues, under the effect of counteracting the estrogen hormone microparticles fully activate in its receptors. This, in turn, leads to a decrease in the activity of pathological tumor cells, and further to their death, which significantly increases the chances of recovery.
The effect of the substance includes recovery of testosterone production, an obstacle to fluid accumulation and a decrease in the index of "harmful" cholesterol.
This drug is considered to be one of the most popular medications that are used to date in the fight against such a pathological condition as breast cancer. Specialists managed to establish that on protein cells of malignant neoplasms, protein substances are often noted, which tend to be associated with female sex hormones, while provoking an increase in the growth of the tumor cell. Through Nolvadex it is possible to block these protein components, and, consequently, to stop the further spread of the malignant neoplasm.
In what kind of disease treatment Nolvadex is helpful?
It is a drug that has earned a lot of positive reviews in the treatment of such pathologies:
• breast cancer in the postmenopausal period;
• endometrial cancer (inner lining of the uterus);
• infertility caused by the lack of maturation of the egg;
• breast cancer in men;
• kidney cancer;
• melanoma (skin cancer).
In special cases, Nolvadex drug is used in the treatment of soft tissue sarcomas and prostate cancer. Despite the positive dynamics of therapy the drug should be used only after consulting a doctor, as it has some contraindications and causes unpleasant, and in some cases, very serious side effects that is why it is important to read the instruction if you buy Generic Nolvadex online.
What should I tell my health care provider before I take Generic Nolvadex?
The main contraindications to taking the drug are:
• pregnancy;
• breast-feeding;
• hypersensitivity to tamoxifen or another component of the drug.
Also, it is worth considering about taking the drug to people suffering from such diseases as:
• kidney failure;
• diabetes;
• eye diseases;
• thrombosis;
• hyperlipidemia;
• lakopenia;
• thrombocytopenia;
• hypercalcemia;
• with the concomitant use of indirect anticoagulants (drugs that reduce the activity of blood coagulation).
Since the use of Nolvadex may aggravate the course of the disease or cause exacerbations of already existing symptoms.
How should I take Nolvadex?
It can be taken before, during, and also after a meal, with a small amount of liquid.
Dosage information
The average dosage is 20-40 mg. Take the drug for a long time. If there is a symptomatic of the progression of the disease, then the medicine is canceled.
What may interact with Generic Nolvadex?
It may be prescribed with other medications. To do this, you need to know how they interact:
With simultaneous administration with anticoagulants there is an increase in anticoagulant effects.
When combined with cytostatics, the likelihood of blood clots increases.
When combined with drugs that lower the excretion of calcium (thiazide diuretics), the probability of an increase in the level of calcium in the blood increases.
Bromocriptine increases the concentration of tamoxifen and N-desmethyltamoxifen in the blood.
In combination with other hormonal agents (estrogen-containing drugs), the therapeutic effect of both drugs is weakened. What should I watch for while taking Nolvadex?
To have a positive effect with no unpleasant symptomatology, it is necessary to follow certain recommendations during therapy:
1. Before the beginning of the therapeutic course, a woman should undergo a thorough diagnosis of gynecologist and therapist.
2. The action of drug positively affects the development of ovulation. This increases the risk of conception of the child. Women of reproductive age need to use reliable methods of contraception, but not hormonal ones. Use them throughout the treatment and within 90 days after the end of the therapeutic course.
3. During treatment, monitor blood coagulation, calcium levels in the blood, plasma images, liver function indicators, blood pressure. Visit the ophthalmologist every 90 days. In case of bloody discharge from the vagina, stop medication.
4. In case of metastasizing to the bone at the initial stage of therapy, it is necessary to monitor the concentration of calcium in the blood serum. If it rises, then stop taking Nolvadex. If the metastases go to the liver, then take the medicine is not effective.
5. If there was a symptomatology of vein thrombosis (pain, swelling), shortness of breath, indicating thromboembolism of the branches of the pulmonary artery, then stop treatment with the drug.
6. In patients with elevated lipid levels in the blood during therapy, monitor the content of cholesterol and TG in the blood serum.
7. During the therapeutic course, carefully drive the car and perform work potentially dangerous, requiring the speed of psychomotor reactions and increased concentration of attention.
What side effects may I notice from Generic Nolvadex?
In the event of a violation of the scheme of application of the drug or in connection with the individual characteristics of the body, the following Nolvadex side effects may appear:
• disorders of the gastrointestinal system;
• dizziness;
• temperature increase;
• a rash on the skin;
• hypercalcemia - an increase in the level of calcium in the blood;
• moderate uterine bleeding;
• thrombosis - the formation of a blood clot in the vessels;
• pathological changes in the retina;
• itching in the genital area;
• increase in body weight.
To date, cases of acute overdose have not been reported. If you use Nolvadex in a higher dosage, then the development of the following symptoms may occur:
dizziness;
hyperreflexion;
tremor;
unsteadiness.
There is no specific antidote. If an overdose occurs, then symptomatic therapy is prescribed.
Where can I keep Nolvadex?
Follow the usual rules of medication storage: in a place with low humidity, far away from children and at a room temperature. You also can buy Nolvadex without prescription in Greece online pharmacy.
