It is a selective modulator of estrogen receptors and is used to prevent the development of osteoporosis during the menopause. It acts on body tissues that do not participate in reproduction as an agonist, but on the reproductive system as an antagonist. The modulator regulates and maintains a normal level of calcium by reducing its excretion in the urine, and also reduces the processes of resorption of bone tissues.
Evista drug is an approved FDA drug to reduce the risk of fractures in osteoporosis. Although it is equally effective in reducing the risk of fractures, like other modern medications, it works only partially by suppressing bone loss.
It does not contribute to the increase in the size of the uterus and does not provoke the proliferation of the endometrium; does not cause bleeding in the postmenopausal period and hyperplasia of breast tissue. The drug helps to reduce soreness and swelling of the mammary glands. The modulator works to reduce cholesterol, fibrinogen in the blood plasma and LDL. Medication, getting inside, immediately absorbed from the stomach and intestines. Within five days a large proportion of the substance remains unchanged from the body with feces and 5% in urine.
It also has the properties of a stimulant for the release of testosterone. In a study on a group of men aged 60-70 years, with a daily dose of 120 mg, the content of testosterone in the serum increased. It can be of value as an addition to a PCT based on hCG. It is a prescription drug but also you can buy it in International Poland Online Pharmacy.
Evista also acts on the production of cholesterol, but to a lesser extent than other drugs. Speaking directly, this is a long-awaited alternative to Tamoxifen.
In what kind of disease treatment Evista is helpful?
Indication for the use of the drug is the possible osteoporosis in women after menopause. There are also studies on its effect on the prevention of cardiovascular diseases, breast cancer, gynecomastia, prostate cancer, acromegaly, and uterine cancer. As an antiestrogen, it will be of interest to bodybuilders to suppress estrogenic side effects.
What should I tell my health care provider before I take Generic Evista?
Contraindicated this modulator is in the presence of the following factors:
•Hypersensitivity;
•Thromboembolism and deep vein thrombosis;
•Endometrial cancer;
•Liver disease (cholestasis);
•Pulmonary embolism;
•Breast cancer;
•Retinal vein thrombosis;
•Uterine bleeding of unknown origin;
•Severe renal impairment.
If you want to buy Evista without prescription then be sure to read the instruction which you can find in the package.
How should I take Evista?
As usual medication in form of tablets it is taken internally.
Dosage information
Treatment is long enough. The daily dose is 60 mg. For elderly there is no need to adjust the dosage. In the case of using athletes to suppress estrogenic side effects from AAS, the dosage is 30-60 mg per day.
What may interact with Generic Evista?
It is not advisable to take both Evista and Colestyramine simultaneously, since the latter reduces the absorption of the modulator and its enterohepatic circulation. Simultaneous reception of Ampicillin reduces the concentration of Raloxifene in the blood plasma, and the rate of elimination and absorption of the drug does not change. Do not combine the modulator with estrogens, as there are no clinical studies for this combination.
What should I watch for while taking Evista?
When Evista is taken, there is an insignificant increase in the concentration of globulins that bind hormones, in particular sex hormones, including increased thyroxine-binding globulin and binding corticosteroids, while increasing the total concentration of hormones. These changes do not affect the amount of free hormones.
In pregnancy Evista is contraindicated as it causes impaired development of the fetus. Along with this, the drug should not be taken during lactation due to possible negative effects on the development of the child. The drug can only be used by women after menopause.
With obvious severe violations of the liver, the drug is not recommended. If, as a result of Evista treatment, a condition results in prolonged immobilization, then the medication should be discontinued. Renewal of therapy is possible after removal of immobilization, restoring all motor functions. During treatment, it is necessary to combine the modulator with calcium-containing drugs. In the event of bleeding, including uterine bleeding, an additional full examination is necessary.
What side effects may I notice from Generic Evista?
If to talk about Evista side effects then there are possible reactions which can occur only if you use it in large amount or you have some health conditions that are not compatible with this medication:
1. Easy thrombocytopenia.
2. Venous thromboembolism.
3. Retinal vein thrombosis.
4. Embolism of the pulmonary artery.
5. Feeling of heat.
6. Peripheral edema.
7. Spasms of the calf muscles.
Where can I keep Evista?
The medication should be stored in a dark and dry place protected from sunlight at an air temperature not exceeding 25 degrees. Storage space should be out of the reach of children. At the end of expiration period, the use of the drug is prohibited. You can also buy Generic Evista which is an excellent way to save on drugs.
