Efudex (Fluorouracil)

What is Generic Efudex?

The international name of the drug is fluorouracil. Pharmacological action of the drug manifests itself in a few hours after the administration of the drug. The result of this effect is oppression of the division of tumor cells. The Efudex instructions for use which is described in this article, is sold in pharmacies in several forms. Only the doctor can determine which of them suits you best. The described agent is available in the form of an ointment, also containing one percent of the active substance.

The drug Efudex, is capable of exerting an anti-inflammatory effect, and also significantly slowing down the chemical reactions leading to the division of malignant tumors. In other words, this substance is capable of blocking the formation of DNA structures.

The active substances of this medication are absorbed very quickly, forming fluorouridine monophosphate. The drug is completely cleaved in the liver in twenty hours. It is excreted by kidneys and respiratory organs.

In what kind of disease treatment Efudex is helpful?

It is prescribed for use in the presence of the following diseases: breast cancer, rectal and colon cancer, pancreatic cancer, esophagus, liver, cervix, ovaries, bladder, prostate, adrenal glands, vulva, penis, skin. Also, medication Efudex collected the best reviews from specialists and patients in the treating of carzion, malignant tumors of the neck and head. A form of ointment is used to treat skin cancer, for example basal.

After one course of therapy, topical application of Efudex cream significantly reduces actinic keratosis.

What should I tell my health care provider before I take Generic Efudex?

Do not take the drug Ftoruracil in the presence of such conditions as:

• Stomatitis;
• Allergy to certain components of fluorouracil;
• Thrombocytopenia, leukopenia, as well as neutropenia;
• Enterocolitis;
• Ulcer, as well as ulcerative colitis.

Caution this medication is prescribed for renal or hepatic insufficiency, acute infectious diseases that have a viral, bacterial origin (tuberculosis, shingles, wind sick pox), bone marrow infiltration by tumor cells.

How should I take Efudex?

It is applied to the skin, on affected areas.

Dosage information

For some patients, doctors prescribe a dosage of 0.6 g / square m. In this case, the medicine should be taken once a week, and treated for two to three months.

If you are prescribed other oncological drugs, then Efudex cream should be applied on the first and eighth day of the course. The required dosage is 0.6 g / m2.

But all the above data are only general recommendations. Do not reduce or increase the dose yourself. This can only be done by your doctor after the necessary examinations. You should read the instruction carefully if you prefer to buy Generic Efudex online.

What may interact with Generic Efudex?

If you are taking any other medicines, do not forget to tell your doctor. After all, this substance cannot be combined with all drugs.

It is not recommended to take medication with phenylbutazone or sulfonamide drugs at the same time. The therapeutic, as well as toxic effect of main substance increases several times with the simultaneous administration of calcium with folinate. With the simultaneous administration with alpha interferon or other cytostatics, toxic and also antitumor effects of Efudex may increase. Metronidazole several times strengthens the toxic effect, especially when it comes to colorectal cancer.

What should I watch for while taking Efudex?

Use of the drug is strictly prohibited during pregnancy. During the treatment, it is necessary to stop breastfeeding. During the reception of the drug contraceptives should be used.

What side effects may I notice from Generic Efudex?

If the rules of application are violated, the following Efudex side effects may occur:

• decreased appetite;
• nausea;
• heartburn;
• vomiting;
• a disturbance in the sense of taste;
• diarrhea;
• impaired liver function;
• deterioration of the blood state, namely - changes in the number of platelets and leukocytes;
• nosebleeds that stop is not so easy;
• Significant visual impairment;
• a constant feeling of nausea, as well as diarrhea and vomiting; if the patient's condition worsens every day, then the doctor must choose another type of therapy;
• myocardial ischemia;
• headache;
• acute cerebellar syndrome;
• bleeding from the digestive tract;
• ulcerative stomatitis;
• confusion;
• cataract;
• neuritis.

In addition, improperly prescribed course may lead to lacrimation, skin rash, bronchospasm, photophobia, dryness and cracks on the skin surface, anaphylactic shock, photophobia, visual impairment, dermatitis, amenorrhea, epistaxis, the development of secondary infections.

Where can I keep Efudex?

It is very important to ensure the right conditions for preserving the medicinal properties of this medication. Find a very dark place with a temperature of about 15-25 degrees Celsius. Do not freeze cream, and keep it away from children.

The drug can be used for two years. The overdue product should not be used further, because in the best case, the drug will not have any effect, and at worst it will make it worse. You can buy Efudex without prescription in one of international pharmacies like Portugal online pharmacy.