Generic Truvada is a drug containing two major components: Emtricitabine (200 mg) and Tenofovir disoproxil (245 mg).
Attention! Truvada is not able to cure a person. It reduces the amount of virus in the blood and keeps it at a low level. This significantly reduces the damage as well as the occurrence of diseases and infections.
Studies have confirmed that the active substances in the combined tablet absorbed and digested by the body as well as in the reception of the two separate medicines with these substances.
In what kind of disease treatmentTruvada is helpful?
What should I tell my health care provider before I takeGeneric Truvada?
Reviews of Generic Truvada shows that it should not be taken in patients with:
hypersensitivity (allergic) to other components of the drug, in particular lactose;
pregnant and lactating females;
children and adolescents under the age of 18 years.
During treatment the women need to use contraceptives to prevent pregnancy. Breast-feeding is contraindicated in patients receiving the drug.
With care preparation is used in these situations:
In existing kidney disease - in this case your doctor may recommend the patient to undergo a study to assess its function. The use of Generic Truvada should be avoided with serious disease, hemodialysis. It is required studies for the purpose of evaluation of renal function.
It will require specific studies to monitor liver function.
How should I take Truvada?
The drug should be taken with food. Tablets should be swallowed whole but people with difficulty swallowing can crush the drug and pour into a glass with one hundred milliliters of water, orange or grape juice.
If you forgot to take a pill, it can be taken later the same day. It is impossible to independently stop taking the drug if the patient concerned about side effects - he should tell his doctor.
What may interact with Generic Truvada?
Notify your doctor if you are taking medicines for kidney.
The combined use of drugs that contain didanosine can lead to a decrease in CD4 cell count. There are reported cases where such mixing resulted in pancreatitis, lactic acidosis and death.
What should I watch for while taking Truvada?
Combined form of the drug is more acceptable because it reduces the number of tablets to one reception per day.
What side effects may I notice from Generic Truvada?
Like any other drug it can cause side effects when it is taken. However, they are shown not in every patient.
hypophosphatemia;
sleep disturbances;
nausea, bloating;
weakness, skin rashes, allergic reactions;
an increase in blood levels of the enzyme creatine kinase;
anemia, pancreatitis;
muscle pain.
Very rare (registered in one out of ten thousand):
Lactic acidosis. Its symptoms may include vomiting, deep or rapid breathing, drowsiness. This is a dangerous condition that can lead to death. Most often it affects women, especially overweight.
Lipodystrophy - irregularities in the distribution of adipose tissue in the body which manifests itself in the form of central obesity, deposition of adipose tissue in the dorsal cervical area with the formation of the so-called buffalo hump, decreasing the fat layer on the extremities, face, breast hypertrophy, Cushingoid appearance (specific distribution of subcutaneous fat, typical for Cushing's disease).
Osteonecrosis (dying off of bone tissue caused by loss of blood supply), whose symptoms include difficulty of movement in the joints, bone pain especially in the shoulders, knees and hips. The risk of osteonecrosis increases with prolonged combination of antiretroviral therapy, corticosteroid use, severe immunosuppression and alcohol use, overweight.
Hyperglycemia (increase in blood glucose level) and the development of insulin resistance due to which the drug should be used with caution in patients with diabetes.
Immune reactivation syndrome (on the background of the recovery of the immune system may increase opportunistic infections), liver damage in patients with viral hepatitis, mitochondrial dysfunction in the child if the mother during pregnancy took Truvada.
