Emflaza (Deflazacort)

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Descrizione

What is Generic Emflaza?

The drug Emflaza is a corticosteroid, whose action is aimed at reducing the inflammatory response and reducing the activity of the immune system. Corticosteroids are used to treat Duchenne muscular dystrophy worldwide, but in the US it has become the first approved corticosteroid drug to treat this disease.

The drug is used in patients with delayed degenerative effects in muscular dystrophy. Reception of drug Emflaza leads to a slowdown of the degenerative effects, contributes to the prevention of cardiac and pulmonary function, delayed the need for an operation on the spine, which is necessary because of the development of scoliosis against the background of atrophy of the muscles of the back.

The effectiveness of the medication was evaluated in clinical trials involving 196 male patients aged 5 to 15 years. At the 12th week of therapy, a clinically significant increase in muscle strength was observed in patients compared with those receiving placebo.

To date, there has not been developed a drug that would cure Duchenne muscular dystrophy, and the current therapy is aimed at slowing the progression of the disease.

In general, the mechanism of the action of Emflaza is as follows: the active ingredient, entering the body, acts on the cells, preventing the release of certain chemicals that cause an aggressive immune (allergic) reaction. With the reception of drug, there is a decrease in the number of white blood cells that can attack the transplanted organ. Therefore, this drug is also used to prevent rejection during transplantation.

The drug, like any other corticosteroid, does not have an analgesic effect, but it affects the very cause of pain - inflammation. Reducing the inflammatory processes, it indirectly and has an analgesic effect, because discomfort in the affected areas are reduced or disappear altogether. Preparations of this group are prescribed in cases when non-steroid drugs have proved ineffective.

In what kind of disease treatment Emflaza is helpful?

This medication is designed to treat Duchenne muscular dystrophy, a rare genetic disease, in patients older than 5 years.

• Anaphylaxis, asthma, severe allergic reactions;

• rheumatoid arthritis, children's chronic arthritis;

• systemic lupus, sarcoidosis;

• rheumatic carditis;

• ulcerative colitis, Crohn's disease;

• autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura;

• acute and lymphatic leukemia, malignant lymphoma.

This is not a complete list. Your doctor can prescribe this medication also for the treatment of other diseases. More detailed information you can get from your physician or if you prefer to buy Generic Emflaza online in the instruction which you can find in the packaging.

The drug can not completely cure muscular dystrophy, but it slows the progression of the disease and reduces symptoms. The drug is well studied and safe with prolonged use.

What should I tell my health care provider before I take Generic Emflaza?

This medication can cause harm to your health if you use it in the following conditions:

• systemic infectious diseases;

• galactose intolerance;

• allergy to steroids.

The whole list of contraindications can give you your doctor and it would be better if he or she will prescribe you this medication after all the tests and with accurate diagnosis.

How should I take Emflaza?

Emflaza pills are taken internally with a glass of any liquid (preferably water). Do not wash down a pill with a grapefruit juice as it may be dangerous to your health.

Dosage information

The optimal dose is 0.9 μg of the drug per kilogram of body weight per day. Some doctors may recommend a daily scheme for taking Emflaza instead of an irregular intake of Prednisone, although the former is significantly more expensive.

What may interact with Generic Emflaza?

It is a new medication and all the interactions may be still not known to us that is why you should inform your doctor about all the medications that you currently take or used to take during last month.

What should I watch for while taking Emflaza?

Patients should strictly follow the treatment regimen to avoid bad consequences. Do not take bigger dosage then it was prescribed by your physician.

As in diseases that can be treated with this medication patients are not recommended to drive it is still worth noting that using this medication you cannot manage the mechanisms that require increased attention.

What side effects may I notice from Emflaza?

The side effects associated with taking Emflaza were similar to those that developed with the use of other corticosteroids. The most common manifestations were swelling of the face, weight gain, increased appetite, upper respiratory tract infection, cough, pollakiuria, and hirsutism.

The most common Emflaza side effects are:

  • symptoms of the cold: nasal congestion, sneezing, sore throat, cough;
  • increase of hairiness of the body;
  • appearance of fatty deposits.

This is not a complete list! There is a risk of developing cataracts and an effect of suppressing growth, but the latter is considered positive for patients with DM. In an irregular scheme, the probability of these manifestations is lower, but still requires constant medical control.

Other undesirable effects that are less common are problems with endocrine function, increased susceptibility to infections, increased blood pressure, and risk of perforation of the gastrointestinal tract, skin rash, and mood changes. In case if you took a larger dosage and notice any symptoms call your doctor or an ambulance.

Where can I keep Emflaza?

The shelf life of drops is 1 year from the production date. Do not use it after the expiration date or if the packaging was damaged. It should be stored in a low humidity and dark place. The temperature should not exceed 25 ° C. Keep the medication far away from kids and animals. It is a prescription medication but it is also available to buy Emflaza without prescription in international pharmacies like Italy online pharmacy.

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Active Ingredient:

Deflazacort

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Active Ingredient