Diovan HCT (Valsartan-hydrochlorothiazide)

Hypertension is one of the most common ailments among the elderly. The disease is characterized by a persistent increase in blood pressure, headaches, general malaise, dizziness, decreased visual acuity. It is dangerous, because with severe development can become the culprit of heart attacks and strokes. Therefore, it is important for patients to comply with the prescribing physician's prescription and take antihypertensive drugs, such as Diovan HCT.

The drug is released on the pharmacological market by Torrent Pharmaceuticals Limited, a recognized world leader in the manufacture of prescription drugs. Diovan HCT drug uses cardiologic practice for more than 8 years, during which time it has earned a good reputation and positive reviews among patients and doctors.

It is a combined medicine, which includes:

• Hydrochlorothiazide - a thiazide diuretic of medium strength.

• Valsartan - angiotensin II receptor blocker, antihypertensive substance.

The drug is characterized by a persistent and rapid therapeutic effect. The effect is noticeable already two hours after taking the medicine, reaches its maximum effect after 5-6 hours and persists throughout the day.

Valsartan is characterized by a wide range of physiological effects, the main of which is the reduction and regulation of blood pressure. It is a powerful vasoconstrictor component, stimulates the secretion of aldosterone. With regular use Valsartan reduces the risk of thrombosis, improves blood circulation and oxygen flow to tissues and brain, and prevents the development of myocardial infarction.

Hydrochlorothiazide has a moderate diuretic effect. It is able to reduce blood pressure changing the reactivity of the vascular wall. In combination with valsartan hydrochlorothiazide enhances the antihypertensive effect. It should be noted that valsartan is one of the most prescribed drugs in cardiac practice. This is due to the extensive experience of application and numerous clinical trials, in which about 135-140 thousand people of different ages and gender participated.

The main indication is hypertension, but it is also can be helpful in lower blood pressure.

• Severe liver disorders (extreme caution in biliary cirrhosis).

• Anuria and other severe pathologies of the kidneys and urinary tract.

• Persistent increase in calcium and potassium in the blood.

• Persistent decrease in potassium or sodium in the blood.

• Period of pregnancy and lactation.

• Hypersensitivity to the components of the drug.

Doctors prescribe patients take this medication internally with a glass of water.

Regardless of the severity of the disease and age, patients are prescribed to take one tablet once a day. The medicine should be taken daily. The duration of the course is selected individually by the attending physician.

Patients with impaired renal or liver function (mild, moderate severity) do not change the dosage.

Before using the drug, it is very important to familiarize yourself with the drug interaction of the components of Diovan HCT, inform the attending physician of all medications taken especially if you prefer to buy Generic Diovan HCT online.

• Caution is required when concurrently consuming potassium-sparing diuretics, due to the risk of hyperkalemia (persistent increase in potassium in the blood).

• Lithium preparations can lead to an irreversible increase in the concentration of lithium in the blood and the occurrence of toxic manifestations (nausea, vomiting, headache, confusion, abdominal pain, etc.).

• During the conducted studies of clinically significant manifestations with taking indomethacin, amlodin, digoxin, atenolol, timentin, furosemide was not recorded. At the same time, there is a potential danger of simultaneous use of these drugs, since Diovan HCT medication contains a thiazide diuretic.

• Curariform means and thiazide diuretics contribute to strengthening the therapeutic effect of each other, increasing the likelihood of an overdose and side effects.

• Non-steroidal anti-inflammatory drugs reduce the antihypertensive effect of Diovan HCT.

• Sularethics, corticosteroids, cabbage, penicillin, salicylic acid increase the risk of hypokalemia.

• Choline blockers (atropine, biperiden) contribute to a decrease in motor activity of the gastrointestinal tract, the appearance of constipation.

• Colestyramin reduces the time of absorption of hydrochlorothiazide.

The drug is prohibited for use during pregnancy and lactation, as its safety and effectiveness in pregnant women and children have not been established to date.

It is known that the use of any ACE inhibitors in the first trimester of pregnancy leads to severe pathologies in fetal development, miscarriage and intrauterine death. In addition, valsartan may be excreted in breast milk and present an increased risk to the health of the baby.

During treatment it is recommended to be careful when driving vehicles.

Diovan HCT side effects with the use of this drug have as a whole a mild and transient nature. These include the following reactions of the body:

1. Paresthesia of the upper or lower extremities.

2. Prolonged headaches.

3. Frequent fatigue.

4. Vertigo.

5. Symptoms of syncope.

6. The onset of an intensified cough.

7. Formation of pulmonary edema of non-cardiogenic nature.

8. Clinically significant decrease in blood pressure.

9. Occurrence of pronounced peripheral edema.

10. Attacks of nausea.

11. Diarrhea occurs.

12. Arthralgia with myalgia.

13. Violation of the normal functioning of the kidneys.

14. The level of uric acid that is contained in the serum increases.

15. Serum increases the number of peasants, as well as bilirubin.

16. Hyponatremia with hypokalemia.

17. Signs of neutropenia.

18. The blood serum increases the content of urea nitrogen.

19. Significant deterioration of vision.

The medicine should be kept in a dry, darkened and inaccessible place for children and pets. Shelf life - up to 3 years. For people who cannot buy medication in the regular pharmacy there is an opportunity to buy Diovan HCT without prescription in USA online pharmacy.