Pamelor (Nortriptyline)

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What is Generic Pamelor?

Due to its action it increases the number of the neurotransmitter serotonin in the synaptic cleft, prolongs and enhances its effect on postsynaptic receptor areas.

This medication is able to affect both the depressive syndrome and its typical symptoms, such as psychomotor retardation, anxiety, depressed mood. Commonly, the clinical effect can be felt after 2-3 weeks of treatment. In addition, Pamelor has a specific effect in the case of treatment of OCD, which differs significantly from the antidepressant effect.

In what kind of disease treatment Pamelor is helpful?

For adult patients:

  • treatment of depression, regardless of origin, which may be accompanied by different symptoms;
  • OCD;
  • phobias, panic attacks;
  • chronic pain syndromes and so on.

For children and adolescents:

  • nocturnal enuresis - for patients from 5 years, in the absence of organic pathology;
  • OCD.

What should I tell my health care provider before I take Generic Pamelor?

Contraindications to taking this medicine are:

  • hypersensitivity to this drug and its components;
  • concomitant use of MAO inhibitors and 2 weeks after cessation of their use;
  • recently transferred MI and so on.

In addition, receiving of this drug is not advised for female patients during pregnancy and breastfeeding, young patients under 15 years of age.

With great care this drug is prescribed in chronic alcoholism, asthma, violations of GI motility, stroke, heart block, kidney and liver failure, urinary retention, schizophrenia, hyperthyroidism, prostatic hyperplasia, prostate, epilepsy in the elderly.

How should I take Pamelor?

Instructions for use Pamelor recommends a single daily oral (internal) taking of pills to patients below the age of 15 years.

Dosage information

This medication is produced in the form of capsules. For the optimal treatment dose adjustments of the drug occurs individually, taking into account the patient's condition. The instructions to the drug indicated that the main goal of treatment is to achieve the maximum effect with the least received doses of the drug, their cautious increase, especially for patients in the elderly and young people who have marked a special sensitivity to Nortriptyline. This course of treatment is established by the attending physician, taking into account changes in the patient's health status.

What may interact with Pamelor?

Simultaneous taking with MAO inhibitors raise the risk of developing serotonin syndrome, as well as other serious adverse effects.

Simultaneous treatment with agents that reduce seizure can lead to seizures.

What should I watch for while taking Pamelor?

To mitigate withdrawal symptoms, the dose should be reduced sequentially during 7-14 days.

The drug can be assigned in 24 hours after discontinuation of treating with MAO inhibitors (reversible), and 14 days if you used irreversible ones.

Consumption of these capsules should be discontinued in the cases when: the manifestation or shortness of epileptic seizures, mania formation and serotonin syndrome.

During the passage of therapy it would be better to avoid driving transport, as well as dangerous work.

What side effects may I notice from Generic Pamelor?

According to specialist's reviews, the symptoms can be of the following types:

  • sweating;
  • dry mouth;
  • constipation;
  • upset stomach;
  • nausea;
  • weight changes;
  • drowsiness / fatigue / irritability / anxiety;
  • not controlled appetite;
  • disorientation in space;
  • confusion / cramps;
  • disturbed sleep mode;
  • mania;
  • urinary retention;
  • blurred vision;
  • Arrhythmia / hypotension / increase in pressure;
  • vomiting / diarrhea;
  • allergic reactions.

Also, there may be unlikely side effects: changes in mental mood, irregular / painful menstruation, muscle rigidity, ringing in the ears, sexual problems, shakiness, tingling of hands and feet. If you have noticed other effects not listed above, contact your doctor or pharmacist.

Possible overdose symptoms include: fast / irregular heartbeat, fainting, severe dizziness, delirium, convulsions and loss of consciousness.

Where can I keep Pamelor?

Keep Pamelor away from children! The place of storage should be dry and dark. Temperature of storage should be below thirty degrees.

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