The active drug substance has an antidepressant effect with a slight sedative and anxiolytic effect. The principle of action of the drug is its high degree of effectiveness of serotonin receptor subtypes. Together with these receptors active substance of the drug interacts at an antagonistic, agonistic level.
Based on the positive feedback Desyrel is a rapidly effective drug that can effectively influence the mental (irritability, anxiety, insomnia, sensing tension) and somatic symptoms of anxiety (palpitations, headaches and muscle pain, frequent urination, excessive sweating, too fast / or deep breathing). It should be noted that the above mentioned medication effectively cope with sleep problems in people with depression. After the course was observed increasing in the depth and duration of sleep and restored its physiological structure and quality.
Thanks to anxiolytic activity a medication Desyrel has a calming effect. The basis of active component of the agent Trazodone eliminates pathogenic factor of occurrence of depression - lack of the hormone serotonin, thereby is achieved the result of antidepressant.
Additionally, the drug is able to remove tachycardia, headache, myalgia, and other symptoms of increased anxiety. At regular taking medication restores the structure of sleep. During treatment also has been observed restoring of the emotional state, decreased harmful alcohol dependence.
Ii is also important that Desyrel is not addictive and does not affect changes in body weight. Canadian online pharmacy offering the best Desyrel.
In what kind of disease treatmentDesyrelis helpful?
The drug is able to stabilize the emotional state, improve mental state, to reduce the craving for alcoholic beverages. It has a result in the treatment of anxiety, depression and sleep disorders.
Trazodone is prescribed:
In libido disorders;
In bulimia;
For the treatment of kleptomania;
Patients with phobias, panic attacks and anxiety;
Anxiety and depression, which have endogenous nature;
What should I tell my health care provider before I takeGeneric Desyrel?
Tablets should not be used:
If you are allergic to Trazodone;
Children up to 6 years;
Intoxication during alcohol or sleeping pills;
Pregnant women;
During lactation.
It is advised to observe caution:
During recovery after myocardial infarction;
In low blood pressure;
Patients with AV-block;
In ventricular fibrillation;
If you have previously experienced priapism;
Liver and kidney diseases;
Under the age of 18 years;
In parallel taking of MAO inhibitors.
How should I take Desyrel?
The tablets should be taken internally after two to four hours after a meal or half an hour before it.
Dosage information
Provided adult dosage is amounting to 100 mg once a day, after a meal before bedtime. It is allowed to increase to a value of the dose of 150 mg on the fourth day. Further rise can be performed every three maybe four days by 50 mg. If a daily dose is bigger than 150 mg then it is necessary to divide it into two doses. For children a dose amount is two / one and a half mg per kilogram per day divided into several times. It can be increased to a volume of 6 mg / kg but following the interval between 3-4 days.
What may interact with Desyrel?
Pseudoephedrine is the combination can cause panic, anxiety, depersonalization. Are described special cases of cardiac arrhythmias in combination of the drug with Amiodarone, reduced anticoagulant activity of Warfarin.
Consumption of medications with Digoxin may lead to increased plasma concentrations of it and the development of cardiac glycoside intoxication. The tablets increase the plasma concentrations of Carbamazepine.
The combination with Lithium salts can cause tremors, neurotoxic effects. The drug is not recommended to combine with ethanol; it strengthens the CNS depression.
Simultaneous treatment with the substance and Thioridazine leads to its increased plasma concentrations. Tryptophan in combination with the drug can cause psychosis, hypomania and aversion to food. Are described isolated cases of increased side effects from taking Phenytoin and Fluoxetine in parallel using of Trazodone.
Trifluoperazine and chlorpromazine may exacerbate hypotension.
What should I watch for while taking Desyrel?
At the time of treatment is allowed the possibility of slight decrease in the level of leucocytes.
There is a probability of bradycardia and decreasing of blood pressure because the drug has a low adrenolytic activity.
Often in people that take medication there is a condition characterized by sudden dizziness and clouding of consciousness after a sharp rise from the bed (orthostatic hypotension).
With extreme caution should be taken medication by patients with illnesses such as ventricular arrhythmia, severe liver and kidney disease, with myocardial infarction, in cases of priapism in the anamnesis as well as in cases of hypersensitivity to the main components of the drug.
Treatment during pregnancy with aforementioned drug is prohibited. Also, women in period of breast-feeding should stop taking the drug.
What side effects may I notice from Generic Desyrel?
Antidepressant Desyrel can cause symptoms such as dizziness, general weakness, sleep disorders, spasms, trembling of the limbs, disturbances in coordination, serotonin intoxication, also are possible imaginary perception, perception without an object, mania, confusion, state of affect, anxiety, upset self-perception, panic attacks.
This is a list of most common side effects:
lowering blood pressure;
dry mouth;
nausea;
drowsiness;
allergic reactions;
orthostatic hypotension;
headache.
Where can I keep Desyrel?
A place when you keep Desyrel should be dry, dark and inaccessible to children at the room temperature.
